32 results found
    1. Neuroscience

    Optogenetic dissection of basolateral amygdala contributions to intertemporal choice in young and aged rats

    Caesar M Hernandez et al.
    Optogenetic approaches in young and aged rats define multiple roles for basolateral amygdala in guiding intertemporal choice, and show that these roles change across the lifespan.
    1. Computational and Systems Biology
    2. Neuroscience

    Time preferences are reliable across time-horizons and verbal versus experiential tasks

    Evgeniya Lukinova et al.
    People have stable time-preferences regardless of whether they are measured using a non-verbal experiential task, as is typical in animal experiments, or using a more traditional verbal task.
    1. Neuroscience

    Dopaminergic neurons write and update memories with cell-type-specific rules

    Yoshinori Aso, Gerald M Rubin
    Building on previous work (Aso et al., 2014a; Aso et al., 2014b), cell-type-specific drivers and optogenetics are used to control the local release of dopamine and reveal that distinct learning rules are implemented in parallel memory units.
    1. Neuroscience

    Leave-One-Trial-Out, LOTO, a general approach to link single-trial parameters of cognitive models to neural data

    Sebastian Gluth, Nachshon Meiran
    Leave-One-Trial-Out (LOTO) is a general, efficient and easily implementable approach for inferring trial-by-trial measures of computational model parameters in order to link these measures to neural mechanisms.
    1. Computational and Systems Biology
    2. Neuroscience

    Fundamental bound on the persistence and capacity of short-term memory stored as graded persistent activity

    Onur Ozan Koyluoglu et al.
    A fundamental lower-bound on memory recall precision, which declines with storage duration and number of stored items, is derived, and human performance is shown to be well-fit by this theoretical bound.
    1. Neuroscience

    Anatomical and functional organization of the human substantia nigra and its connections

    Yu Zhang et al.
    The human substantia nigra can be parcellated into three subdivisions that subserve emotional, cognitive and somatomotor function.
    1. Neuroscience

    Ultra-Rapid serial visual presentation reveals dynamics of feedforward and feedback processes in the ventral visual pathway

    Yalda Mohsenzadeh et al.
    Reducing visibility with higher image presentation rates increases recurrent processing demands along the visual processing pathway to resolve object recognition.
    1. Neuroscience
    2. Computational and Systems Biology

    A specific role for serotonin in overcoming effort cost

    Florent Meyniel et al.
    A selective reuptake inhibitor shows a beneficial effect in healthy humans during an effort-benefit tradeoff task, mediated at the computational level by a specific alleviation of effort cost.
    1. Neuroscience

    Reward-based training of recurrent neural networks for cognitive and value-based tasks

    H Francis Song et al.
    A two-part neural network models reward-based training and provides a unified framework in which to study diverse computations that can be compared to electrophysiological recordings from behaving animals.
    1. Neuroscience

    Uncertainty leads to persistent effects on reach representations in dorsal premotor cortex

    Brian M Dekleva et al.
    When Rhesus monkeys plan reaching movements of which they are not fully confident, a particular area of the brain represents both the chosen action as well as alternate movements, perhaps as an aid for error correction or learning.

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