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    1. Neuroscience

    Noradrenaline release from the locus coeruleus shapes stress-induced hippocampal gene expression

    Mattia Privitera, Lukas M von Ziegler ... Johannes Bohacek
    Targeted manipulation of the locus coeruleus noradrenaline circuitry combined with extensive transcriptomic analyses in the mouse hippocampus reveal a unique set of noradrenaline-dependent, stress-related genes and point to astrocytic engagement.
    1. Computational and Systems Biology
    2. Developmental Biology

    How enhancers regulate wavelike gene expression patterns

    Christine Mau, Heike Rudolf ... Ezzat El-Sherif
    An experimental and computational system has been developed to investigate how wavelike gene expression patterns are generated during embryonic development.
    1. Computational and Systems Biology
    2. Neuroscience

    Attention stabilizes the shared gain of V4 populations

    Neil C Rabinowitz, Robbe L Goris ... Eero P Simoncelli
    Populations of neurons in the macaque visual cortex are subject to shared fluctuations in gain; these signals exhibit anatomical and functional structure, and their variability is diminished under attention.
    1. Cell Biology
    2. Plant Biology

    Natural variation reveals that intracellular distribution of ELF3 protein is associated with function in the circadian clock

    Muhammad Usman Anwer, Eleni Boikoglou ... Seth Jon Davis
    In Arabidopsis, a natural variant of the ELF3 protein, which originated in Central Asia, is less likely to accumulate in the nucleus, and causes the circadian clock to run faster and be less responsive to environmental cues.
    1. Evolutionary Biology

    Spatial and temporal distribution of ribosomes in single cells reveals aging differences between old and new daughters of Escherichia coli

    Lin Chao, Chun Kuen Chan ... Ulla Camilla Rang
    Differences in the ribosomal densities of the two daughters produced by a mother Escherichia coli could explain the asymmetry of aging and growth rate in previously reported such daughter pairs.
    1. Neuroscience

    Amplitude modulations of cortical sensory responses in pulsatile evidence accumulation

    Sue Ann Koay, Stephan Thiberge ... David W Tank
    From as early as primary visual cortex and across posterior cortical areas, neural responses to visual pulses during an evidence-accumulation task exhibit a multitude of task-related amplitude modulations/gain changes.
    1. Evolutionary Biology

    Convergent evolution of small molecule pheromones in Pristionchus nematodes

    Chuanfu Dong, Cameron J Weadick ... Ralf J Sommer
    Unexpected structural diversity of nematode small molecules, as revealed by high-resolution phylogenetic analysis, suggests recurrent biochemical innovation, a pattern that is probably typical across animals.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Persistence, period and precision of autonomous cellular oscillators from the zebrafish segmentation clock

    Alexis B Webb, Iván M Lengyel ... Andrew C Oates
    Time-lapse recording and theoretical analysis of individual cells isolated from the zebrafish segmentation clock reveal that they behave as self-sustained, autonomous oscillators with distinctive noisy dynamics.
    1. Neuroscience

    Ultra-Rapid serial visual presentation reveals dynamics of feedforward and feedback processes in the ventral visual pathway

    Yalda Mohsenzadeh, Sheng Qin ... Dimitrios Pantazis
    Reducing visibility with higher image presentation rates increases recurrent processing demands along the visual processing pathway to resolve object recognition.
    1. Neuroscience

    Dopaminergic modulation of the exploration/exploitation trade-off in human decision-making

    Karima Chakroun, David Mathar ... Jan Peters
    Dopamine attenuates exploration during decision-making via a reduction of neural tracking of uncertainty.