The findings have a major impact in understanding the different reward systems involved in two types of addictive behavior, and these advances have implications for prevention and treatment.
Leave-One-Trial-Out (LOTO) is a general, efficient and easily implementable approach for inferring trial-by-trial measures of computational model parameters in order to link these measures to neural mechanisms.
Ramesh Chittajallu, Kurt Auville ... Chris J McBain
Similar to their mouse counterparts, human neurogliaform cells that comprise a specialized from of inhibitory neuron, possess the ability to modulate their intrinsic excitability in response to ongoing network activity.
Cognitive effort is aversive and people will accept physical pain to avoid it, but this avoidance does not appear to share the same fundamental characteristics of pain avoidance.
Behavioural evidence and computational analyses suggest that people tend to decline the pursuit of more rewarded goals because they, wrongly, expect them to require more effortful actions.
