946 results found
    1. Epidemiology and Global Health

    A case study for a psychographic-behavioral segmentation approach for targeted demand generation in voluntary medical male circumcision

    Sema K Sgaier, Maria Eletskaya ... Steve Kretschmer
    A novel, hybrid segmentation technique reveals human heterogeneity in barriers towards a behavior, and is applied to characterize distinct segments in voluntary medical male circumcision.
    1. Neuroscience

    Uncertainty-based inference of a common cause for body ownership

    Marie Chancel, H Henrik Ehrsson, Wei Ji Ma
    Behavioral and computational results show that the perception of our body as our own depends on Bayesian probabilistic reasoning that take into account the variations in sensory uncertainty when integrating visual and somatosensory cues.
    1. Cell Biology

    Mitochondrial flashes regulate ATP homeostasis in the heart

    Xianhua Wang, Xing Zhang ... Heping Cheng
    Mitochondrial flashes counteract the imbalance of ATP supply-and-demand and constitute an auto-regulator of ATP homeostasis in the heart.
    1. Cell Biology
    2. Neuroscience

    Dendritic mitochondria reach stable positions during circuit development

    Michelle C Faits, Chunmeng Zhang ... Daniel Kerschensteiner
    Mitochondria reach stable positions in dendrites during a critical developmental period of high motility.
    1. Structural Biology and Molecular Biophysics

    Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2

    Dari Kimanius, Björn O Forsberg ... Erik Lindahl
    Using GPUs for the costly computations in cryo-EM enables structure determination in mere days on a single workstation.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism

    Anirban Roy, Meiricris Tomaz da Silva ... Ashok Kumar
    The IRE1/XBP1 signaling in myofibers is essential for robust skeletal muscle regeneration in response to injury.
    1. Cell Biology

    Spatial transcriptomics reveals metabolic changes underly age-dependent declines in digit regeneration

    Robert J Tower, Emily Busse ... Mimi C Sammarco
    Metabolic supplementation attenuates age-dependent declines in regeneration.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Intrinsic adaptive value and early fate of gene duplication revealed by a bottom-up approach

    Guillermo Rodrigo, Mario A Fares
    Gene duplication is a useful strategy to reduce intrinsic noise in gene expression, which can provide a selective advantage in scenarios of cost-benefit analysis of expression.
    1. Medicine
    2. Neuroscience

    Cold protection allows local cryotherapy in a clinical-relevant model of traumatic optic neuropathy

    Yikui Zhang, Mengyun Li ... Wencan Wu
    Local deep hypothermia combined with hibernation-mimicking cold protection is neuroprotective in a translatable large animal model of traumatic optic neuropathy.
    1. Neuroscience

    Integrated externally and internally generated task predictions jointly guide cognitive control in prefrontal cortex

    Jiefeng Jiang, Anthony D Wagner, Tobias Egner
    The dorsolateral prefrontal cortex integrates concurrent externally and internally generated predictions of task demand to guide information processing, while the medial prefrontal cortex corrects its prediction error based on actual task demand.

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