Sarah E Canetta, Emma S Holt ... Christoph Kellendonk
Prefrontal PV interneuron activity during development is necessary for prefrontal circuit maturation, supporting adult prefrontal network function and cognitive flexibility.
Nicolas Michalski, Juan D Goutman ... Christine Petit
Targeted mutations in a Ca2+-binding site of otoferlin, a transmembrane protein of synaptic vesicles defective in a recessive form of deafness, reveal its Ca2+ sensor role both for vesicle fusion and vesicle pool replenishment.
Ian A Clark, Siawoosh Mohammadi ... Eleanor A Maguire
A new magnetic resonance brain imaging measure reveals that variations in people’s ability to recall their past experiences may be related to the speed at which electrical signals travel along axons in the parahippocampal cingulum bundle.
Neurite geometry enables expansive and highly-branched neuronal structures to operate like single electrical compartments and simple linear integrators.
Travis A Hage, Alice Bosma-Moody ... Gabe J Murphy
A combination of multicellular recording and optogenetic photostimulation was used to deeply characterize the spatial profiles and effective strengths of intralaminar and translaminar synaptic connections from genetically defined neuronal populations in the visual cortex of adult mouse.
Neuroligin 1 is a critical adhesion molecule which organizes AMPA receptor nanodomains in close vicinity to pre-synaptic release sites, and whose genetic or chemical disruption severely impairs synaptic transmission properties.