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    1. Neuroscience

    The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells

    Fugui Niu, Peng Han ... Sheng-Jian Ji
    The m6A reader YTHDF2 negatively regulates retinal ganglion cell dendrite branching through destabilizing its m6A-modified target mRNAs which control dendrite development and maintenance, and Ythdf2 conditional knockout in retina improves visual acuity and alleviates acute ocular hypertension-induced glaucoma in mice.
    1. Developmental Biology
    2. Neuroscience

    Presynaptic contact and activity opposingly regulate postsynaptic dendrite outgrowth

    Emily L Heckman, Chris Q Doe
    Opposing mechanisms determine dendrite arbor size during a critical period in Drosophila.
    1. Cell Biology
    2. Developmental Biology

    Growth cone-localized microtubule organizing center establishes microtubule orientation in dendrites

    Xing Liang, Marcela Kokes ... Kang Shen
    In Caenorhabditis elegans, dendrites establish their unique microtubule polarity by localizing an organizing center behind the growing tip.
    1. Developmental Biology
    2. Neuroscience

    Inter-organ Wingless/Ror/Akt signaling regulates nutrient-dependent hyperarborization of somatosensory neurons

    Yasutetsu Kanaoka, Koun Onodera ... Yukako Hattori
    A muscle-derived Wnt signal promotes dendritic branching of somatosensory neurons in response to a concurrent deficiency in vitamins, minerals, and cholesterol.
    1. Cell Biology
    2. Developmental Biology

    Patronin governs minus-end-out orientation of dendritic microtubules to promote dendrite pruning in Drosophila

    Yan Wang, Menglong Rui ... Fengwei Yu
    A minus-end-binding stabilizes minus-end-out microtubules in dendrites, which are required for dendrite-specific pruning during neuronal remodelling.
    1. Developmental Biology
    2. Neuroscience

    Cannabinoid-induced actomyosin contractility shapes neuronal morphology and growth

    Alexandre B Roland, Ana Ricobaraza ... Zsolt Lenkei
    Cannabinoids inhibit neuronal expansion and growth through the rapid contraction of actomyosin.
    1. Neuroscience

    A multicellular rosette-mediated collective dendrite extension

    Li Fan, Ismar Kovacevic ... Zhirong Bao
    Migrating skin carries the amphid rosette vertex anteriorly to extrude and position dendrites.
    1. Developmental Biology

    Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal extension and steering via activating an autoregulatory factor, Mtss1

    Namsuk Kim, Yan Li ... Won-Jong Oh
    Repulsive guidance cues enhance a dual-functioning axonal trafficking facilitator, allowing navigating axons to ensure proper pathfinding by coordinating positive extension and negative steering during nervous system development.
    1. Neuroscience

    A conserved morphogenetic mechanism for epidermal ensheathment of nociceptive sensory neurites

    Nan Jiang, Jeffrey P Rasmussen ... Jay Z Parrish
    Epidermal cells in vertebrates and invertebrates ensheath portions of somatosensory neurons via a conserved morphogenetic mechanism, and this ensheathment regulates morphogenesis and function of Drosophila nociceptive neurons.
    1. Neuroscience

    Self-organization of modular network architecture by activity-dependent neuronal migration and outgrowth

    Samora Okujeni, Ulrich Egert
    Activity-dependent neurite outgrowth and neuronal migration interact to shape modular mesoscale network architecture by homeostatic self-organization.