620 results found
    1. Neuroscience

    Non-linear dimensionality reduction on extracellular waveforms reveals cell type diversity in premotor cortex

    Eric Kenji Lee et al.
    WaveMAP is a novel approach that combines nonlinear dimensionality reduction with graph clustering on extracellular waveforms to reveal previously obscured cell type diversity in monkey cortex.
    1. Neuroscience

    Synaptotagmin 7 is targeted to the axonal plasma membrane through γ-secretase processing to promote synaptic vesicle docking in mouse hippocampal neurons

    Jason D Vevea et al.
    Synaptotagmin 7 is asymmetrically localized to the axonal plasma membrane through γ-secretase processing to promote vesicle docking during short-term synaptic plasticity in mouse hippocampal neurons.
    1. Developmental Biology
    2. Neuroscience

    Maturation of Purkinje cell firing properties relies on neurogenesis of excitatory neurons

    Meike E van der Heijden et al.
    Intersectional genetics show that excitatory neurons are essential for the functional and anatomical maturation of cerebellar circuits in mice.
    1. Developmental Biology
    2. Neuroscience

    Spinal lumbar dI2 interneurons contribute to stability of bipedal stepping

    Baruch Haimson et al.
    Spinal dI2 interneurons relay peripheral and intraspinal feedback to premotor networks in the spinal cord and the cerebellum to ensure the stability of bipedal stepping.
    1. Cell Biology
    2. Neuroscience

    Glycolytic preconditioning in astrocytes mitigates trauma-induced neurodegeneration

    Rene Solano Fonseca et al.
    Promoting a Warburg-like shift in astrocytic metabolism through reduced mitochondrial electron transport accommodates the energetic burden caused by brain trauma without overwhelming cellular respiration and redox to salvage dopaminergic neurons.
    1. Neuroscience

    Classification and genetic targeting of cell types in the primary taste and premotor center of the adult Drosophila brain

    Gabriella R Sterne et al.
    A split-GAL4 collection provides precise genetic targeting of 138 neuronal cell types in the subesophageal zone of adult Drosophila melanogaster.
    1. Cell Biology
    2. Developmental Biology

    Whole-organism 3D quantitative characterization of zebrafish melanin by silver deposition micro-CT

    Spencer R Katz et al.
    Melanin staining for micro-CT imaging, using a novel application of ionic silver deposition, enables qualitative and quantitative 3D analysis of zebrafish pigmentation and reveals subtle phenotypes missed by light microscopy.
    1. Cell Biology
    2. Neuroscience

    The amyloid precursor protein is a conserved Wnt receptor

    Tengyuan Liu et al.
    The amyloid precursor protein known for its role in causing familial Alzheimer's disease directly interacts with secreted proteins, called Wnts, known for their key roles in brain development and homeostasis, suggesting the two processes may be directly linked.
    1. Neuroscience

    Activity-dependent regulation of mitochondrial motility in developing cortical dendrites

    Catia AP Silva et al.
    Naturally occurring activity in the developing brain regulates mitochondrial motility such that mitochondria stop at active synapses, which is probably a fundamental process in brain wiring.
    1. Neuroscience

    Systematic morphological and morphometric analysis of identified olfactory receptor neurons in Drosophila melanogaster

    Cesar Nava Gonzales et al.
    A morphological characterization of Drosophila olfactory receptor neurons—conducted systematically at nanoscale resolution—yields an extensive morphometric dataset, identifies novel features of olfactory sensilla, and raises intriguing questions for how the size and shape of sensory neurons influence their function.

Refine your results by:

Type
Research categories