Browse the search results

Page 2 of 65
    1. Neuroscience

    Nanoconnectomic upper bound on the variability of synaptic plasticity

    Thomas M Bartol Jr et al.
    Spine heads on the same dendrite receiving input from the same axon are the same size.
    1. Neuroscience

    Dendritic nonlinearities are tuned for efficient spike-based computations in cortical circuits

    Balázs B Ujfalussy et al.
    Dendrites combine the inputs that they receive from other neurons using calculations that have been optimized for those particular input patterns.
    1. Cell Biology
    2. Neuroscience

    Astrocytes refine cortical connectivity at dendritic spines

    W Christopher Risher et al.
    Spines with multiple excitatory contacts are potential sites for competition between thalamic and cortical axons, which is regulated by the astrocytes through the secreted synaptogenic protein hevin.
    1. Computational and Systems Biology
    2. Neuroscience

    Inhibition enhances spatially-specific calcium encoding of synaptic input patterns in a biologically constrained model

    Daniel B Dorman et al.
    Inhibition enhances the spatial specificity of high calcium influx for cooperatively stimulated synapses, suggesting that inhibitory inputs may regulate both synapse-specific and heterosynaptic plasticity to support learning and memory.
    1. Cell Biology
    2. Neuroscience

    Ablation of SNX6 leads to defects in synaptic function of CA1 pyramidal neurons and spatial memory

    Yang Niu et al.
    SNX6 regulates the distribution of a protein called Homer1b/c to distal dendrites, enabling the latter to stabilize the synapses and thereby support memory formation.
    1. Neuroscience

    Loss of Cdc42 leads to defects in synaptic plasticity and remote memory recall

    Il Hwan Kim et al.
    Conditional knockout of the small GTPase Cdc42 in excitatory neurons of the mouse forebrain leads to impaired long-term synaptic plasticity and impaired retrieval of remote memory.
    1. Developmental Biology
    2. Neuroscience

    EphrinB2 regulates VEGFR2 during dendritogenesis and hippocampal circuitry development

    Eva Harde et al.
    The internalization of the angiogenic receptor VEGFR2 expressed in neurons is controlled by ephrinB2 and is required for neuronal dendritic arborization, spine morphogenesis and circuitry development in the hippocampus.
    1. Neuroscience

    High and asymmetric somato-dendritic coupling of V1 layer 5 neurons independent of visual stimulation and locomotion

    Valerio Francioni et al.
    Layer 5 neuron apical tuft in mouse visual cortex display widespread, highly correlated calcium signals, with a strong and asymmetric coupling to somatic signals, independent of visual stimulation and locomotion.
    1. Neuroscience

    The fate of hippocampal synapses depends on the sequence of plasticity-inducing events

    J Simon Wiegert et al.
    Non-invasive optogenetic induction of synaptic plasticity revealed that long-term potentiation and long-term depression alter the chances of a synapse to survive the next seven days.
    1. Neuroscience

    Pedunculopontine glutamatergic neurons control spike patterning in substantia nigra dopaminergic neurons

    Daniel J Galtieri et al.
    Pedunculopontine neurons can evoke burst spiking in substantia nigra dopaminergic neurons without engaging a subtype of glutamate receptor previously thought to be necessary for this spiking mode.