1,177 results found
    1. Neuroscience

    Supramammillary nucleus synchronizes with dentate gyrus to regulate spatial memory retrieval through glutamate release

    Yadong Li et al.
    Multi-fiber photometry recording and circuit-based manipulation in vivo identify a long-range SuM-DG circuit linking two highly correlated subcortical regions to regulate spatial memory retrieval through SuM glutamate transmission.
    1. Neuroscience

    Entrained neuronal activity to periodic visual stimuli in the primate striatum compared with the cerebellum

    Masashi Kameda et al.
    Neurons in the striatum exhibited periodic firing in monkeys attempting to detect omission of repetitive visual stimulus, while the phase of neuronal activity differed from that observed in the cerebellum.
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Phase Separation: Restricting the sizes of condensates

    Furqan Dar, Rohit Pappu
    Computer simulations of model proteins with sticker-and-spacer architectures shed light on the formation of biomolecular condensates in cells.
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    1. Neuroscience

    Learning: The cerebellum influences vocal timing

    Court Hull
    We are starting to understand how the cerebellum contributes to vocal learning in songbirds.
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    1. Cancer Biology

    Oncogene Regulation: Enhancers not required

    Ying Zheng, David Levens
    Laboratory mice with over half a megabase of DNA upstream of their Myc gene removed still thrive in the absence of stress.
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  1. Point of View: Telling it like it is

    Alison Woollard
    Following a year of public engagement activities associated with the Royal Institution Christmas Lectures, Alison Woollard explains why scientists need to communicate with the public.
    1. Structural Biology and Molecular Biophysics

    Protein Unfolding: Same structure, different mechanisms?

    Francis TF Tsai, Christopher P Hill
    Two interpretations of similar structures for the same molecular machine illustrate the limits of inferring biochemical mechanism from protein structure.
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    1. Developmental Biology

    Addressing the ethical issues raised by synthetic human entities with embryo-like features

    John Aach et al.
    Guidelines governing research into embryos need to be updated in a way that reflects the moral status of synthetic human entities generated using the methods of synthetic biology.
    1. Biochemistry and Chemical Biology

    Science Forum: Donated chemical probes for open science

    Susanne Müller et al.
    A collaboration between several pharmaceutical companies provides a unique resource of high-quality chemical probes and associated data from the companies to the academic community.

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