28 results found
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Single Cell Transcriptomics-Informed Induced Pluripotent Stem Cells Differentiation to Tenogenic Lineage

    Angela Papalamprou, Victoria Yu ... Dmitriy Sheyn
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Developmental Biology
    2. Evolutionary Biology

    A distinct cardiopharyngeal mesoderm genetic hierarchy establishes antero-posterior patterning of esophagus striated muscle

    Glenda Comai, Eglantine Heude ... Shahragim Tajbakhsh
    Tbx1-Isl1-Met defines a unique genetic hierarchy that regulates esophagus myogenesis and patterning in the mouse.
    1. Cell Biology
    2. Developmental Biology

    Perirenal adipose tissue contains a subpopulation of cold-inducible adipocytes derived from brown-to-white conversion

    Houyu Zhang, Yan Li ... Meng Xie
    A brown-to-white adipogenic transdifferentiation process in the periureter region of mouse renal adipose tissue gives rise to a population of cold-inducible adipocytes with a transcriptome distinct from subcutaneous beige adipocytes.
    1. Developmental Biology
    2. Neuroscience

    Semaphorin7A patterns neural circuitry in the lateral line of the zebrafish

    Agnik Dasgupta, Caleb C Reagor ... AJ Hudspeth
    Semaphorin7A sculpts the collective arbor architecture of the lateral line nerve and facilitates neural contacts with the hair cells for synaptogenesis during neuromast development in the zebrafish.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Distinct origins and molecular mechanisms contribute to lymphatic formation during cardiac growth and regeneration

    Dana Gancz, Brian C Raftrey ... Karina Yaniv
    Cardiac lymphatic vessels of heterogeneous origins and molecular signatures support cardiac growth and regeneration.
    1. Developmental Biology

    Completion of neural crest cell production and emigration is regulated by retinoic-acid-dependent inhibition of BMP signaling

    Dina Rekler, Chaya Kalcheim
    BMP-dependent retinoic acid signaling is responsible for the separation of central from peripheral lineages during neural development.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Myogenin is an essential regulator of adult myofibre growth and muscle stem cell homeostasis

    Massimo Ganassi, Sara Badodi ... Simon M Hughes
    Cellular and molecular analyses reveal how Myogenin controls muscle stem cell quiescence and growth of adult muscle fibres.
    1. Developmental Biology
    2. Evolutionary Biology

    Logics and properties of a genetic regulatory program that drives embryonic muscle development in an echinoderm

    Carmen Andrikou, Chih-Yu Pai ... Maria Ina Arnone
    A gene regulatory network model provides a simplified explanation of the molecular interactions that orchestrate muscle development in the sea urchin embryo.
    1. Developmental Biology

    SRSF2 is a key player in orchestrating the directional migration and differentiation of MyoD progenitors during skeletal muscle development

    Rula Sha, Ruochen Guo ... Ying Feng
    Genetic mouse models combined with single-cell RNA sequencing reveal the essential role of SRSF2 in directing MyoD progenitors to distinct skeletal muscle domains and controlling their differentiation through the regulation of targeted genes and alternative splicing during skeletal muscle development.
    1. Cell Biology

    Control of brown adipose tissue adaptation to nutrient stress by the activin receptor ALK7

    Patricia Marmol, Favio Krapacher, Carlos F Ibáñez
    The activin receptor ALK7 regulates the adaptation of brown adipose tissue to nutrient availability by preventing over-activation of signaling pathways induced by fasting, allowing appropriate response to cold exposure.

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