Conditional silencing of long ascending propriospinal neurons disrupts interlimb coordination of the fore and hindlimb pairs, but in a highly context-specific manner.

A brain descending interneuron can coordinate a switch between two antagonistic behaviors (forward and backward locomotions).

The reconstruction of a sensorimotor pathway from the olfactory-sensory neurons down to the pre-motor system reveals a descending neuron that plays a critical role in the organization of larval chemotaxis.

Systematic analysis of descending neuron anatomy reveals the basic functional map of descending sensory-motor pathways in flies and provides genetic tools for targeted interrogation of neural circuits.

The neurons that connect the brain and ventral nerve cord in fruit flies have been mapped in unprecedented detail.

The identification of a neural circuit that drives a specific grooming movement in Drosophila reveals that it may also control movement parameters, such as duration.

Parabrachial neurons expressing CGRP relay affective components of ascending pain information via distinct thalamic and amygdalar pathways, which together contribute to complementary aspects of adaptive threat responses.

A decoding-based, state-space reconstruction reveals that neurons in macaque IT cortex change the structure of their collective attractor dynamics depending on task contexts.

Neurophysiological and behavioral approaches reveal how coordinated input from descending pathways shapes the tuning properties of electrosensory neurons in order to optimize coding of natural stimuli through temporal whitening.

Optogenetically activated individual descending neurons in Drosophila melanogaster drive varied stereotyped motor patterns that are often influenced by the animal's initial behavioral state.