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    1. Developmental Biology

    Differential regulation of cranial and cardiac neural crest by serum response factor and its cofactors

    Colin J Dinsmore, Philippe Soriano
    A novel allele of serum response factor (SRF) reveals distinct co-factor requirements in different developmental contexts, raising issues of redundancy, threshold requirements, or novel co-factor usage.
    1. Neuroscience

    Separable neural signatures of confidence during perceptual decisions

    Tarryn Balsdon, Pascal Mamassian, Valentin Wyart
    Neural processes for perception and confidence can be separated thanks to computational electroencephalography, thus revealing a neural circuit specific to metacognition.
    1. Neuroscience

    Does slow oscillation-spindle coupling contribute to sleep-dependent memory consolidation? A Bayesian meta-analysis

    Thea Ng, Eunsol Noh, Rebecca MC Spencer
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Incomplete
    1. Neuroscience

    Massive cortical reorganization in sighted Braille readers

    Katarzyna Siuda-Krzywicka, Łukasz Bola ... Marcin Szwed
    Teaching a tactile alphabet to sighted adults reveals the brain’s unexpected potential for change.
    1. Neuroscience

    Altered topology of neural circuits in congenital prosopagnosia

    Gideon Rosenthal, Michal Tanzer ... Galia Avidan
    An innovative inter-subject stimulus-locked brain activation approach uncovers marked topological differences in a brain network of higher-order visual regions in individuals with a congenital impairment in face recognition compared with controls.
    1. Neuroscience

    Evidence for dopaminergic involvement in endogenous modulation of pain relief

    Simon Desch, Petra Schweinhardt ... Susanne Becker
    Endogenous modulation of pain relief perception is based on its motivational content and enhanced by increased dopamine availability with no significant effects of a pharmacological opioidergic manipulation in healthy volunteers.
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Epigenetic signature of human immune aging in the GESTALT study

    Roshni Roy, Pei-Lun Kuo ... Luigi Ferrucci
    Identification of human DNA sites differentially methylated with aging across six different primary immune cells suggests that the sensing of hypoxia drives the epigenetic clock.
    1. Developmental Biology

    Identification and characterization of intermediate states in mammalian neural crest cell epithelial to mesenchymal transition and delamination

    Ruonan Zhao, Emma L Moore ... Paul A Trainor
    Epithelial to mesenchymal transition (EMT) is a continuous process, in which the transition or intermediate states can be molecularly and spatially defined, shedding new light on development and disease EMT.
    1. Neuroscience

    Effects of nicotine compared to placebo gum on sensitivity to pain and mediating effects of peak alpha frequency

    Samantha K. Millard, Alan K.I. Chiang ... David A. Seminowicz
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Exposing distinct subcortical components of the auditory brainstem response evoked by continuous naturalistic speech

    Melissa J Polonenko, Ross K Maddox
    The response from discrete stages of the early auditory pathway can be measured by subtle manipulations to long-form natural speech stimuli paired with deconvolution analysis of electroencephalography data.