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    1. Computational and Systems Biology
    2. Neuroscience

    Theoretical principles explain the structure of the insect head direction circuit

    Pau Vilimelis Aceituno, Dominic Dall'Osto, Ioannis Pisokas
    Three theoretical principles explain the neural activity observed in the head direction circuit of insects, the connectivity pattern underlying the circuit, and how the ubiquitous eight-column circuit structure emerged from evolutionary processes.
    1. Cell Biology
    2. Neuroscience

    Unraveling the link between neuropathy target esterase NTE/SWS, lysosomal storage diseases, inflammation, abnormal fatty acid metabolism, and leaky brain barrier

    Mariana I Tsap, Andriy S Yatsenko ... Halyna R Shcherbata
    Drosophila model reveals that NTE/SWS-associated neurodegeneration is a lysosomal storage disorder accompanied by a leaky brain permeability barrier, abnormal fatty acid metabolism, and inflammation.
    1. Plant Biology

    Improving rice drought tolerance through host-mediated microbiome selection

    Alex Styer, Dean Pettinga ... Devin Coleman-Derr
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Ecology

    Warming and altered precipitation independently and interactively suppress alpine soil microbial growth in a decadal-long experiment

    Yang Ruan, Ning Ling ... Zhibiao Nan
    Warming and altered precipitation reduce the growth rates of alpine soil bacteria by 40-90%, and the growth of ~70% taxa is influenced by antagonistic interactions between factors.
    1. Neuroscience

    Sensorimotor mechanisms selective to numerosity derived from individual differences

    Giovanni Anobile, Irene Petrizzo ... Guido Marco Cicchini
    Evidence for a selective sensorimotor brain mechanism responsible for translating sensory numerical information into the number of actions in a sequence.
    1. Computational and Systems Biology
    2. Neuroscience

    Endotaxis: A neuromorphic algorithm for mapping, goal-learning, navigation, and patrolling

    Tony Zhang, Matthew Rosenberg ... Markus Meister
    A neural circuit model reveals how biological brains may implement rapid learning and navigation in complex spaces.
    1. Immunology and Inflammation

    Tailoring Tfh profiles enhances antibody persistence to a clade C HIV-1 vaccine in rhesus macaques

    Anil Verma, Chase E Hawes ... Smita S Iyer
    Strategies to enhance Tfh cells for HIV-vaccine antibody persistence and protection is pivotal for vaccine success.
    1. Ecology
    2. Plant Biology

    Unprecedented yet gradual nature of first millennium CE intercontinental crop plant dispersal revealed in ancient Negev desert refuse

    Daniel Fuks, Yoel Melamed ... Ehud Weiss
    New archaeobotanical data from Negev Highland rubbish middens demonstrate that crop diversity in the Southern Levant expanded more during the first millennium CE than in any earlier period, yet with minimal consequences for consumption and production patterns.
    1. Plant Biology

    Glutaredoxin regulation of primary root growth is associated with early drought stress tolerance in pearl millet

    Carla de la Fuente, Alexandre Grondin ... Laurent Laplaze
    Increased primary root growth in pearl millet is correlated with early water stress tolerance, an important constraint in agrosystems in the Sahel, and is associated with the regulation of root cell elongation by a glutaredoxin.
  1. Line drawing of a human figure sitting on a stylised brain, in front of white sparks on a lilac background. Vicky Bowskill (CC BY-NC-ND 4.0)

    Being Neurodivergent in Academia: Outgrowing self-denial

    Jay K Goldberg
    After hitting rock bottom a few months into a prestigious fellowship, a postdoc recounts how they found their way to ADHD medication, therapy, and better mental health.