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    1. Chromosomes and Gene Expression
    2. Neuroscience

    SNORD90 induces glutamatergic signaling following treatment with monoaminergic antidepressants

    Rixing Lin, Aron Kos ... Gustavo Turecki
    A small non-coding RNA, SNORD90, links monoaminergic directed antidepressant treatment with glutamatergic activation.
    1. Cancer Biology

    Mice deficient of Myc super-enhancer region reveal differential control mechanism between normal and pathological growth

    Kashyap Dave, Inderpreet Sur ... Jussi Taipale
    A tumor-specific regulatory region has been identified upstream of the Myc oncogene.
    1. Neuroscience

    A projectome of the bumblebee central complex

    Marcel Ethan Sayre, Rachel Templin ... Stanley Heinze
    Serial-section electron microscopy uncovers the intricate neural network of the bumblebee central complex, revealing highly conserved projection patterns as well as novel circuit elements potentially unique to bees.
    1. Cancer Biology

    Gene interaction perturbation network deciphers a high-resolution taxonomy in colorectal cancer

    Zaoqu Liu, Siyuan Weng ... Xinwei Han
    An individual-specific gene interaction perturbation network-based (GIN) approach reveals six stable GIN subtypes (GINS1-6) with distinguishing and high-resolution features.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Kinetic sculpting of the seven stripes of the Drosophila even-skipped gene

    Augusto Berrocal, Nicholas C Lammers ... Michael B Eisen
    Live quantitative monitoring of transcriptional bursting reveals that enhancers responding to different regulators use the same kinetic strategy to produce a complex composite pattern of developmental expression.
    1. Plant Biology

    Improving rice drought tolerance through host-mediated microbiome selection

    Alex Styer, Dean Pettinga ... Devin Coleman-Derr
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Plant Biology

    Antimicrobial peptide expression in a wild tobacco plant reveals the limits of host-microbe-manipulations in the field

    Arne Weinhold, Elham Karimi Dorcheh ... Ian T Baldwin
    The attempt to manipulate a microbiome in planta to study the ecological consequences under field conditions leaves plants and their microbes surprisingly unimpressed.
    1. Ecology
    2. Evolutionary Biology

    Desiccation resistance differences in Drosophila species can be largely explained by variations in cuticular hydrocarbons

    Zinan Wang, Joseph P Receveur ... Henry Chung
    Evolutionary changes in cuticular hydrocarbons, a lipid layer on the insect epicuticle, underlie the evolution of desiccation resistance in Drosophila species.
    1. Ecology

    Sequential phenotypic constraints on social information use in wild baboons

    Alecia J Carter, Miquel Torrents Ticó, Guy Cowlishaw
    Social information is a process encompassing information acquisition, application and exploitation that is constrained by an individual’s social, behavioural and demographic phenotype.
    1. Cancer Biology
    2. Computational and Systems Biology

    Comprehensive characterization of tumor microenvironment in colorectal cancer via molecular analysis

    Xiangkun Wu, Hong Yan ... Li Liang
    Integrated molecular analysis demonstrated that colorectal cancer can be classified into four molecular subtypes (proliferative, immunomodulatory, immunosuppressed, and immune-excluded subtypes), providing valuable insight into the intricate relationship between tumor microenvironment heterogeneity and various clinical phenotypes.