5,893 results found
    1. Evolutionary Biology

    Decoupled maternal and zygotic genetic effects shape the evolution of development

    Christina Zakas et al.
    Early development involves both maternal and zygotic genetic effects. This dual genetic basis shapes the evolution of developmental mode in a marine annelid.
    1. Developmental Biology
    2. Evolutionary Biology

    Evolution of limb development in cephalopod mollusks

    Oscar A Tarazona et al.
    Cuttlefish embryos reveal that cephalopod mollusks evolved specialized arms and tentacles by activating the same genetic circuits that control development of limbs in arthropods and vertebrates.
    1. Genetics and Genomics

    Ancient mechanisms for the evolution of the bicoid homeodomain's function in fly development

    Qinwen Liu et al.
    Transgenic animals carrying reconstructed ancestral alleles reveal how two ancient mutations allowed a regulatory protein to evolve a controlling role in embryonic development in flies.
    1. Developmental Biology
    2. Evolutionary Biology

    A novel enhancer near the Pitx1 gene influences development and evolution of pelvic appendages in vertebrates

    Abbey C Thompson et al.
    Regulatory sequences downstream of a key limb identity gene are required for normal sizes of leg bones, and are changed in wild species with dramatic alterations in pelvic structures.
    1. Developmental Biology

    Developmental evolution of the forebrain in cavefish, from natural variations in neuropeptides to behavior

    Alexandre Alié et al.
    A comparative approach shows that developmental evolution of neuropeptidergic neuronal groups in the hypothalamus of blind cavefish drives adaptive behavioral evolution.
    1. Developmental Biology
    2. Evolutionary Biology

    Evolution of Segmentation: Sox enters the picture

    Felix Kaufholz, Natascha Turetzek
    The discovery of a gene that regulates two segmentation mechanisms in spider embryos is fueling the ongoing debate about the evolution of this crucial developmental process.
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    1. Developmental Biology
    2. Evolutionary Biology

    An ancient yet flexible cis-regulatory architecture allows localized Hedgehog tuning by patched/Ptch1

    David S Lorberbaum et al.
    The seemingly simple, constitutive response of the patched/Ptch1 gene to Hedgehog signaling is in fact regulated by large batteries of context-specific Hedgehog-responsive enhancers in both fly and mouse, allowing tissue-specific tuning of the Hedgehog pathway in animal development and evolution.
    1. Developmental Biology
    2. Evolutionary Biology

    Maternally regulated gastrulation as a source of variation contributing to cavefish forebrain evolution

    Jorge Torres-Paz et al.
    Phenotypic evolution can originate from variations in very precocious developmental events, starting even before fecundation, during the fabrication of the egg in the mother's gonad.
    1. Developmental Biology
    2. Evolutionary Biology

    Developmental variability channels mouse molar evolution

    Luke Hayden et al.
    The nature and extent of developmental variation seen between mouse strains and genetically identical individuals explain why the first upper molar evolves along preferred path in murine rodents.
    1. Developmental Biology
    2. Evolutionary Biology

    Long-distance communication by specialized cellular projections during pigment pattern development and evolution

    Dae Seok Eom et al.
    Cells of the xanthophore lineage form projections that allow them to communicate with other pigment cells during adult pigment pattern formation in zebrafish, but not in the closely-related pearl danio.

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