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Free, extracellular dispersal of Wnt proteins generates a long-range gradient during animal development and is required for signaling.

New views on the relevance of bone morphogenetic protein signalling fine tuning in the cardiac neural crest cells for the heart outflow tract septation and the formation of the great arteries.

A theory predicts whether diffusion or direct transport establishes a more precise morphogen profile, and this prediction explains data from a wide variety of morphogens in two different organisms.

Human brain suggests an asymmetric organization along a functional cortical axis describing a hierarchical functional trajectory from perceptual/action to abstract cognition, which is heritable and comparable with macaque brain, suggesting (phylo)genetic conservation and adaptation.

The tip-link complex of the hair cell is mechanically tuned along the tonotopic axis of the cochlea.

The Fat/Dachsous/Four-jointed (Ft/Ds/Fj) system provides a spatial signal to organize core PCP proteins via the polarization of microtubules.

Gene regulatory networks incorporate information of the embryonic geometrical parameters to give rise to differential individual patterning outputs under decanalized genetics backgrounds.

The diversification of hand bones in mammals was much more dynamic than those of the proximal and intermediate forearm, involving higher morphological diversity, stronger integration, and greater evolutionary lability at distal structures.

Opposing gradients of Fat and Dachsous phosphorylation are sufficient to explain the observed pattern of Fat-Dachsous planar polarisation across the Drosophila wing.

A new probabilistic model of connectivity reveals the structural and functional properties of the neural networks controlling locomotion in many individual tadpoles.