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Timely regulation of growth cone dynamics, including filopodial and cytoskeletal rearrangements through phosphorylation signals from glial cells, shapes the photoreceptor axon targeting.

An unbiased biochemical screen reveals a direct link between gene regulation and actin cytoskeleton remodeling.

Knockdown of PHOX2B in the chemosensitive area of the retrotrapezoid nucleus of adult rats reduces CO₂ responses and the expression of the proton sensors TASK2 and GPR4.

Interactions between Neuropilin-1 and VEGFR2, rather than VEGF-Neuropilin-1 binding, underlie Neuropilin-1's critical function in VEGF-mediated vascular development.

The great pond snail is a multipurpose model organism and a contemporary choice for addressing a wide range of biological questions, problems and phenomena in the laboratory and the field.

Gab1 is a key downstream effector of PDGF signaling and essential to oligodendrocyte differentiation by linking PDGF signaling with GSK3β/β-catenin module.

Ultrastructural and loss-of-function experiments show that oligodendrocyte-encoded Kir4.1 is located near active axonal structures, including within myelin inner tongue, and has critical functions to promote axonal activity and preserve integrity.

Neuronal progenitor cells autonomously inhibit polarization via the transcription factor Zeb1.

Photoreceptors diversify their target field at long range through a graded signal.

The Notch signaling pathway has a central role in the development of the nervous system, and also in the establishment of networks of connections in the adult brain