2,068 results found
    1. Developmental Biology
    2. Physics of Living Systems

    Cerebellar folding is initiated by mechanical constraints on a fluid-like layer without a cellular pre-pattern

    Andrew K Lawton et al.
    A multi-phase wrinkling model accounts for the radial and circumferential tension and differential expansion between a uniformly proliferating outer fluid-like layer and an incompressible core that together drive cerebellar folding.
    1. Developmental Biology

    Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation

    Maria R Stupnikov et al.
    Notch ligands from the Delta and Jagged families have distinct roles in epithelial progenitor cell fate of extrapulmonary and intrapulmonary airways and differentially restrict expansion of the neuroendocrine microenvironment.
    1. Computational and Systems Biology

    Science Forum: Wikidata as a knowledge graph for the life sciences

    Andra Waagmeester et al.
    Wikidata is continuously-updated resource that could improve the efficiency and accuracy of research in many areas of the life and biomedical sciences.
    1. Evolutionary Biology
    2. Physics of Living Systems

    Morphogenesis: Mathematical models with frills

    Pierre A Haas
    The spectacular frill around the neck of the lizard Chlamydosaurus has its origins in a mechanical instability that arises during development.
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    1. Epidemiology and Global Health

    Science Forum: Unit of analysis issues in laboratory-based research

    Nick R Parsons et al.
    A simulation study is used to demonstrate how mistakes in identifying the experimental unit and the unit of analysis can lead to incorrect analyses and inappropriate inferences when reporting research studies.
    1. Evolutionary Biology
    Baboon illustration

    The Natural History of Model Organisms: Insights into the evolution of social systems and species from baboon studies

    Julia Fischer et al.
    Wild baboons are an excellent model to study complex evolutionary processes such as speciation and hybridization, as well as the links between sociality, longevity and reproductive success.
  1. Research: Decoupling of the minority PhD talent pool and assistant professor hiring in medical school basic science departments in the US

    Kenneth D Gibbs Jr et al.
    A systems-level analysis of the biomedical workforce in the US shows that current strategies to enhance faculty diversity are unlikely to have a significant impact, and that there is a need to increase the number of PhDs from underrepresented minority backgrounds who move on to postdoctoral positions.
    1. Developmental Biology

    Addressing the ethical issues raised by synthetic human entities with embryo-like features

    John Aach et al.
    Guidelines governing research into embryos need to be updated in a way that reflects the moral status of synthetic human entities generated using the methods of synthetic biology.
    1. Epidemiology and Global Health
    2. Immunology and Inflammation

    Science Forum: A Global lmmunological Observatory to meet a time of pandemics

    Michael J Mina et al.
    The COVID-19 pandemic has clearly demonstrated the need for a global system to monitor the dynamics of susceptibility and immunity, as well as infection, during epidemics and pandemics.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Science Forum: The Brazilian Reproducibility Initiative

    Olavo B Amaral et al.
    Researchers are undertaking a systematic assessment of the reproducibility of biomedical science in Brazil.

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