Genetic and molecular analyses reveal the decisive role of fatty acid oxidation (FAO) acting downstream to the ROS-JNK circuit essential for hemocyte progenitor differentiation in Drosophila..
The timing of sexual differentiation in the brain of the nematode Caenorhabditis elegans is controlled by a phylogenetically conserved pathway of gene regulatory factors.
Wnt signaling regulates cellular redox in the germline stem cell differentiation niche via a novel regulatory mechanism, thereby controlling germ line stem cell progeny differentiation.
Compliant matrix provides a permissive micoenvironment for cardiomyocyte dedifferentiation, cell division and expansion, and thus may open a new avenue towards cardiac regeneration.
A novel complex composed of various components of a chromatin remodeling complex, a chromatin remodeling factor and a transcription factor suppresses the dedifferentiation of intermediate neural progenitors back into neuroblasts in Drosophila.
During ES cell differentiation, Yap1 directly regulates apoptosis-related genes like Bcl-2 and Mcl-1 to attenuate apoptosis and promote cell survival to allow for successful cell fate changes.
GAS5 is related to osteoporosis by regulating the differentiation of bone marrow stromal cells that acts as a promising treatment target for osteoporosis.