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    1. Neuroscience

    Rapid categorization of natural face images in the infant right hemisphere

    Adélaïde de Heering, Bruno Rossion
    Diverse photographs of human faces against their natural background trigger a specific electrical response in the right hemisphere of the brain in infants aged 4–6 months.
    1. Neuroscience

    Increasing stimulus similarity drives nonmonotonic representational change in hippocampus

    Jeffrey Wammes, Kenneth A Norman, Nicholas Turk-Browne
    Hippocampal learning in dentate gyrus follows a U-shaped function, with moderate, but not high or low, overlap between representations leading to differentiation of neural patterns.
    1. Computational and Systems Biology
    2. Developmental Biology

    Constructing and optimizing 3D atlases from 2D data with application to the developing mouse brain

    David M Young, Siavash Fazel Darbandi ... Stephan J Sanders
    A computational tool developed to construct three-dimensional anatomical atlases from two-dimensional data generates volumetrically complete and aligned atlases for all stages of development in the Allen Developing Mouse Brain Atlas.
    1. Neuroscience
    2. Physics of Living Systems

    Gigapixel imaging with a novel multi-camera array microscope

    Eric E Thomson, Mark Harfouche ... Eva A Naumann
    A new multi camera imaging platform simultaneously captures large-area, high-resolution video of unconstrained small model organisms and provides behavioral measurements that span multiple spatial scales.
    1. Computational and Systems Biology
    2. Neuroscience

    Bumblebee visual allometry results in locally improved resolution and globally improved sensitivity

    Gavin J Taylor, Pierre Tichit ... Emily Baird
    Bigger bumblebee eyes have better vision, yet their field of view, sensitivity, and resolution do not all simply scale up with eye size, being improved locally instead.
    1. Computational and Systems Biology
    2. Medicine

    Personalized computational heart models with T1-mapped fibrotic remodeling predict sudden death risk in patients with hypertrophic cardiomyopathy

    Ryan P O'Hara, Edem Binka ... Natalia A Trayanova
    Personalized virtual-heart technology for arrhythmia risk assessment could transform the management of hypertrophic cardiomyopathy patients, eliminating many unnecessary primary-prevention defibrillator deployments while ensuring patients at high risk for arrhythmia are adequately protected.
    1. Stem Cells and Regenerative Medicine

    An optogenetic cell therapy to restore control of target muscles in an aggressive mouse model of amyotrophic lateral sclerosis

    J Barney Bryson, Alexandra Kourgiantaki ... Linda Greensmith
    Stem-cell-based neural replacement, in combination with optogenetic stimulation, could represent a translationally viable therapeutic strategy to overcome atrophy and paralysis of targeted muscles in people living with amyotrophic lateral sclerosis.
    1. Cancer Biology

    Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells

    Lan-Feng Dong, Jaromira Kovarova ... Jiri Neuzil
    A genetic approach documents that mitochondrial DNA moves from donor cells to recipient mtDNA-depleted cells in whole mitochondria and that this restores mitochondrial respiration and the capacity of the cells to form tumours.
    1. Developmental Biology

    Multiscale cardiac imaging spanning the whole heart and its internal cellular architecture in a small animal model

    Graham Rykiel, Claudia S López ... Sandra Rugonyi
    Correlative imaging of the heart at multiple spatial scales has the potential to revolutionize the way we understand deficiencies in congenital heart disease.
    1. Developmental Biology

    Computational 3D histological phenotyping of whole zebrafish by X-ray histotomography

    Yifu Ding, Daniel J Vanselow ... Keith C Cheng
    X-ray histotomography produces the first 3-dimensional images with the combined submicron resolution, centimeter fields-of-view, soft-tissue contrast, and potential throughput to enable quantitative, histopathological and centimeter-scale phenotyping for whole-organism phenomics.