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Page 2 of 202
    1. Developmental Biology

    Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling

    Megan L Norris, Andrea Pauli ... Alexander F Schier
    Elucidation of direct and indirect roles of GPCR signaling during gastrulation.
    1. Developmental Biology
    2. Neuroscience

    Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition

    Shalini Singh, Danielle Howell ... David J Solecki
    Neuronal progenitor cells autonomously inhibit polarization via the transcription factor Zeb1.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Ankyrin-B is a PI3P effector that promotes polarized α5β1-integrin recycling via recruiting RabGAP1L to early endosomes

    Fangfei Qu, Damaris N Lorenzo ... Vann Bennett
    Ankyrin-B – through interactions with PI3P lipids, dynactin and RabGAP1L – functions as a critical node in the protein circuitry underlying polarized recycling of α5β1-integrin to enable haptotaxis along fibronectin gradients.
    1. Immunology and Inflammation

    Elevated glycolytic metabolism of monocytes limits the generation of HIF1A-driven migratory dendritic cells in tuberculosis

    Mariano Maio, Joaquina Barros ... Luciana Balboa
    A newly identified immunometabolic mechanism clarifies the aberrant trafficking of dendritic cells to lymph nodes in tuberculosis.
    1. Cell Biology
    2. Physics of Living Systems

    Neutrophils actively swell to potentiate rapid migration

    Tamas L Nagy, Evelyn Strickland, Orion D Weiner
    Actin-independent water influx complements actin-driven cytoskeletal forces to potentiate chemoattractant-induced migration in primary human neutrophils.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Translational regulation of protrusion-localized RNAs involves silencing and clustering after transport

    Konstadinos Moissoglu, Kyota Yasuda ... Stavroula Mili
    RNAs enriched at cell protrusions are translated regardless of their location in the cytoplasm but are dynamically repressed in retracting protrusions and incorporated into heterogeneous RNA clusters.
    1. Physics of Living Systems

    Cells use molecular working memory to navigate in changing chemoattractant fields

    Akhilesh Nandan, Abhishek Das ... Aneta Koseska
    Combined experimental and theoretical analysis identifies a molecular mechanism akin to working memory that enables single cells to perform complex navigation tasks in changing growth factor fields, beyond simple stimulus-response associations.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Spatial modulation of individual behaviors enables an ordered structure of diverse phenotypes during bacterial group migration

    Yang Bai, Caiyun He ... Xiongfei Fu
    Bacterial population can coordinate individuals of different phenotypes by spatial modulation of their run-and-tumble behaviors, resulting in collective group migration with an ordered structure of phenotypes.
    1. Developmental Biology
    2. Neuroscience

    Intermediate progenitors support migration of neural stem cells into dentate gyrus outer neurogenic niches

    Branden R Nelson, Rebecca D Hodge ... Robert F Hevner
    Multiphoton live-imaging illuminates the dynamic underpinnings of how different types of progenitor cells migrate and interact to robustly build the mammalian Dentate Gyrus neural circuitry and new outer neurogenic niche.
    1. Cell Biology
    2. Developmental Biology

    Zebrafish fin regeneration involves generic and regeneration-specific osteoblast injury responses

    Ivonne Sehring, Hossein Falah Mohammadi ... Gilbert Weidinger
    Osteoblast dedifferentiation and migration are injury responses that are differentially regulated and independent of regenerative bone formation.