Experimental and computational models reveal how parallel 'core' mechanisms shape direction selectivity at the dendrites of starburst amacrine cells and ganglion cells in the mouse retina.

Synapse-specific genetic manipulations show that distinct GABAergic inputs are differentially recruited to encode motion direction in the retina in a stimulus-dependent manner.

ON and OFF visual motion is computed with the same algorithm despite differences in circuit architecture.

Emx2 mediates the directional selectivity of neuromasts by regulating hair bundle orientation in hair cells, and by selecting afferent neuronal targets.

A common mechanism for computation of direction selectivity in the ON and OFF channel is demonstrated.

Uniting two principles that have been thought of being mutually exclusive in the past can explain how neurons become sensitive to the direction of motion.

Two photon calcium imaging experiments show that excitatory and inhibitory neurons in the mouse superior colliculus are differentially modulated by the motion contrast between stimulus center and surround.

Accurate direction-selective information is present within small sections of the dendrites, raising the possibility that single dendrites utilize parallel processing schemes to process motion information.

Patterning of dendrites by protocadherin-dependent self-avoidance and self/non-self discrimination is required for proper function of a retinal circuit that computes the direction of motion.