The rhythmicity in upper-limb tracking movements and associated population dynamics in primary motor cortex is explained by a feedback controller incorporating optimal state estimation.
Damien Jullié, Camila Benitez ... Mark von Zastrow
Quantitative imaging of neurons reveals how opioid agonists produce long-term functional tolerance at presynaptic terminals through rapid internalization of receptors from the axonal surface.
Deciphering the dynamics of the allosteric communication and the formation of transient pockets along the activation pathway of G-protein-coupled receptors provides useful information for the design of allosteric modulators.
Anna Anchimiuk, Virginia S Lioy ... Stephan Gruber
Bacterial chromosome folding by DNA loop extrusion is here shown to rely on avoidance of SMC collisions by low SMC abundance, clustering of loading sites, efficient translocation, and rare unloading.
Jian-You Lin, Narendra Mukherjee ... Donald B Katz
Blocking input from basolateral amygdala to gustatory cortex (GC) severely reduces the coherence of GC ensemble activity, which negatively affects epochal dynamics involved in driving palatability-driven consumption.
