6,504 results found
    1. Cell Biology
    2. Developmental Biology

    Optogenetic investigation of BMP target gene expression diversity

    Katherine W Rogers, Mohammad ElGamacy ... Patrick Müller
    Optogenetic manipulation of BMP signaling indicates that diversity in BMP-dependent gene expression is not well explained by differential responses to BMP, and combinatorial signaling is a major driver of diversity.
    1. Neuroscience

    Task-related hemodynamic responses in human early visual cortex are modulated by task difficulty and behavioral performance

    Charlie S Burlingham, Minyoung Ryoo ... Elisha P Merriam
    The fMRI-BOLD signal in human early visual cortex reflects alertness and behavioral performance on the timescale of individual trials.
    1. Neuroscience

    5'-UTR SNP of FGF13 causes translational defect and intellectual disability

    Xingyu Pan, Jingrong Zhao ... Xu Zhang
    A 5'-UTR SNP of FGF13 impairs PTBP2 interacting with FGF13 mRNA, leading to reduced FGF13 translation and deficits in brain development and cognitive functions.
    1. Computational and Systems Biology

    A convolutional neural network for the prediction and forward design of ribozyme-based gene-control elements

    Calvin M Schmidt, Christina D Smolke
    Machine learning has been applied to develop predictive models for designing RNA gene-control elements with targeted gene-regulatory activities.
    1. Neuroscience

    Vicarious reward unblocks associative learning about novel cues in male rats

    Sander van Gurp, Jochen Hoog ... Marijn van Wingerden
    Rats learn to interpret cues predicting rewards delivered to social partners as valuable, but only if social information exchange is possible.
    1. Neuroscience

    Body ownership promotes visual awareness

    Björn van der Hoort, Maria Reingardt, H Henrik Ehrsson
    Inducing illusory ownership of a fake hand increases the perceptual dominance of that hand during binocular rivalry.
    1. Neuroscience

    Quantifying decision-making in dynamic, continuously evolving environments

    Maria Ruesseler, Lilian Aline Weber ... Laurence Tudor Hunt
    Human behaviour in a continuous decision making task adapts to the overall statistics of the sensory environment, and these adaptations are also reflected in changes in neural responses to incoming sensory evidence.
    1. Microbiology and Infectious Disease

    The Plasmodium falciparum apicoplast cysteine desulfurase provides sulfur for both iron-sulfur cluster assembly and tRNA modification

    Russell P Swift, Rubayet Elahi ... Sean T Prigge
    Plasmodium falciparum apicoplast SufS is required for both iron-sulfur synthesis and tRNA modification by MnmA, a novel paradigm that is likely to apply to other plastid-containing organisms.
    1. Cancer Biology
    2. Chromosomes and Gene Expression

    Co-regulation and function of FOXM1/RHNO1 bidirectional genes in cancer

    Carter J Barger, Linda Chee ... Adam R Karpf
    FOXM1 is co-expressed with its bidirectional gene partner RHNO1, and the two genes promote DNA repair, cell growth and survival, and chemotherapy resistance in ovarian cancer.
    1. Epidemiology and Global Health

    Inference of the SARS-CoV-2 generation time using UK household data

    William S Hart, Sam Abbott ... Robin N Thompson
    Updated estimates of the generation time of SARS-CoV-2 infections indicate that the generation time has become shorter.

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