Natanael Spisak, Gabriel Athènes ... Aleksandra M Walczak
HILARy is a new algorithm for grouping B-cell receptor sequences into distinct lineages, a crucial task to analyze immune response and memory through repertoire sequencing.
Johanna Odenwald, Bernardo Gabiatti ... Susanne Kramer
Proteins that are low abundant and/or poorly accessible to antibodies can be readily localised with fluorescent streptavidin, when expressed fused to a biotin ligase.
Changes in the amount and timing of gene expression during early development contribute to evolutionary divergence and life-history changes, even within a species.
Analysis of mouse zygotic genome activation (ZGA) reveals that a mis-annotated multicopy homeobox gene Obox4 functions redundantly with Dux to promote ZGA.
Magdalena Podkowik, Andrew I Perault ... Bo Shopsin
A new framework for examining tolerance in the context of quorum-sensing that may ultimately help predict and manage bacterial tolerance and, therefore, improve clinical outcome during infection.
Laure Mignerot, Clotilde Gimond ... Christian Braendle
Caenorhabditis elegans egg-laying behaviour shows pronounced variation in natural populations, making it a promising model to investigate the microevolution of a simple neural circuit.
Exploring tissue-specific regulation of gene expression with human-chimpanzee hybrid cells helps us understand how life evolves and what makes us human.
