Browse the search results

Gene copy number provides more prognostic information than gene mutation status in cancer.

Transcription factors of the ETS family govern a cohort of key cancer-associated regulators of malignancy in squamous cell carcinomas.

HILARy is a new algorithm for grouping B-cell receptor sequences into distinct lineages, a crucial task to analyze immune response and memory through repertoire sequencing.

CRISPR knock-outs and functional genomic approaches probe the regulatory mechanism restricting the Hox gene Ubx to butterfly hindwings, explaining color pattern differentiation from forewings.

Mutations in the TRIM5α retrovirus-binding interface frequently improve but rarely disrupt retroviral restriction.

Neural crest and placode lineages both contribute to the enteric nervous system, divergently utilizing Edn3-Ednrb and GDNF-Ret signaling.

The light-activated plant photoreceptor phytochrome A binds to NOT9B to displace it from the CCR4-NOT complex, thereby de-repressing light signalling.

RNA-binding proteins use both translational activation and repression of key molecular determinants to post-mitotically sculpt the identity and connectivity of developing mouse neocortex in an area-specific manner.

A proper balance of planar and perpendicular balances is critical to establishing proper epidermal architecture and is mediated by the opposing activities of LGN and its enigmatic paralog AGS3.

A computational systems biology approach identifies a gene network module associated with single-cell mechanical phenotype changes across diverse mouse and human systems, with implications for on-demand engineering of cell stiffness.