Jorge Blanco Mendana, Margaret Donovan ... Daryl M Gohl
A method for genetically barcoding Drosophila is developed and used to tag defined cell populations in vivo for single-cell transcriptomics experiments and to enable multiplexed behavioral analysis.
Nathan M Shugarts Devanapally, Aishwarya Sathya ... Antony M Jose
Transport of double-stranded RNA from parental circulation to progeny using the transmembrane protein SID-1 can occur through multiple routes during C. elegans development and buffer heritable changes in gene expression.
Audrey Le Veve, Mathieu Genete ... Vincent Castric
By modulating the intensity of balancing selection at the S-locus, dominance between self-incompatibility alleles shapes the genetic load linked to each allele, creating inbreeding depression in some S-locus homozygotes.
Pre-hematopoietic stem cells emerge from the aortic floor according to two radically different morphodynamics whose biomechanics rely on controlling apicobasal polarity in hemogenic precursors, which may impact on their fate.
Strong reduction in malaria transmission by genetically modified mosquitoes is achieved in the laboratory using a dual gene drive that simultaneously propagates an antiparasitic factor and a parasite-detrimental mosquito mutation.
