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    1. Neuroscience

    Irregular spiking of pyramidal neurons organizes as scale-invariant neuronal avalanches in the awake state

    Timothy Bellay et al.
    Spontaneous, irregular spiking in single cortical pyramidal neurons assembles as neuronal avalanches at the group level identifying a robust scale-invariant organization of resting activity in the awake state.
    1. Neuroscience

    Pruriception and neuronal coding in nociceptor subtypes in human and nonhuman primates

    Amanda Klein et al.
    MRGPRD and MRGRPX1 are co-expressed in primate DRG neurons, but β-alanine and BAM8-22, preferentially activate CMH-subclasses, and co-activating different cutaneous nociceptors by pruritogens does not change itch sensation to pain.
    1. Neuroscience

    A spinoparabrachial circuit defined by Tacr1 expression drives pain

    Arnab Barik et al.
    A circuit involving Tacr1-expressing neurons in the spinal cord and the parabrachial nucleus controls how mice respond to a wide range of persistently painful stimuli.
    1. Neuroscience

    Responding to preconditioned cues is devaluation sensitive and requires orbitofrontal cortex during cue-cue learning

    Evan E Hart et al.
    The orbitofrontal cortex is necessary for learning about value-neutral sensory associations to impact subsequent model-based behavior.
    1. Neuroscience

    In vivo functional diversity of midbrain dopamine neurons within identified axonal projections

    Navid Farassat et al.
    Midbrain dopamine neurons function according to their axonal projections in the intact brain.
    1. Neuroscience

    Visualizing endogenous opioid receptors in living neurons using ligand-directed chemistry

    Seksiri Arttamangkul et al.
    Opioid sensitive neurons were identified using a traceless affinity labeling strategy to covalently label endogenous mu-opioid receptors with fluorescent compounds in living brain slices from wild type animals.
    1. Immunology and Inflammation

    TLR5 participates in the TLR4 receptor complex and promotes MyD88-dependent signaling in environmental lung injury

    Salik Hussain et al.
    The response to TLR4 ligands in mice and humans is modulated by TLR5, which participates in the TLR4 signaling complex.
    1. Neuroscience

    Brainstem network dynamics underlying the encoding of bladder information

    Anitha Manohar et al.
    Neural and network activity within a pontine-cortical micturition circuit are finely coordinated with urodynamics to assure appropriate voiding behaviors.
    1. Neuroscience

    Preconditioned cues have no value

    Melissa J Sharpe et al.
    Preconditioned cues provide information about an associative model but do not, by default, trigger representations of value, either model-based or model-free.