674 results found
    1. Epidemiology and Global Health

    Urinary metabolic biomarkers of diet quality in European children are associated with metabolic health

    Nikos Stratakis, Alexandros P Siskos ... Leda Chatzi
    Urinary metabolic signatures relate to adherence to the Mediterranean diet and ultra-processed food intake in childhood and reflect associations of these diet quality indicators with metabolic health.
    1. Neuroscience

    Knockdown of PHOX2B in the retrotrapezoid nucleus reduces the central CO2 chemoreflex in rats

    Silvia Cardani, Tara A Janes ... Silvia Pagliardini
    Knockdown of PHOX2B in the chemosensitive area of the retrotrapezoid nucleus of adult rats reduces CO2 responses and the expression of the proton sensors TASK2 and GPR4.
    1. Computational and Systems Biology
    2. Neuroscience

    Normative decision rules in changing environments

    Nicholas W Barendregt, Joshua I Gold ... Zachary P Kilpatrick
    In environments that fluctuate over the course of deliberation, optimal decision strategies display novel dynamics that can explain human response behaviors better than commonly used alternatives.
    1. Neuroscience

    Effects of clozapine-N-oxide and compound 21 on sleep in laboratory mice

    Janine Traut, Jose Prius Mengual ... Lukas B Krone
    The two most commonly used chemogenetic actuators, clozapine-N-oxide and compound 21, similarly modulate sleep in wild-type laboratory mice indicating that even designer drugs which do not convert to clozapine can elicit behavioural effects and require adequate controls.
    1. Neuroscience

    Synaptic learning rules for sequence learning

    Eric Torsten Reifenstein, Ikhwan Bin Khalid, Richard Kempter
    Through mathematical analysis and computer simulations, the neuronal underpinnings of feasible models of sequence learning are delineated.
    1. Neuroscience

    The landscape of regulatory genes in brain-wide neuronal phenotypes of a vertebrate brain

    Hui Zhang, Haifang Wang ... Jie He
    Single-cell transcriptomes of larval zebrafish whole brain shed light on the multidimensional landscapes of transcription factors and post-transcriptional regulators in vertebrate whole-brain neuronal classification and revealed principles of how neuronal cell diversity develops and evolves.
    1. Cell Biology
    2. Neuroscience

    Activity-dependent Golgi satellite formation in dendrites reshapes the neuronal surface glycoproteome

    Anitha P Govind, Okunola Jeyifous ... William N Green
    Neuronal activity triggers the dispersal of the Golgi into dendritic Golgi satellites, leading to reshaping of the neuronal surface glycoproteome through processing of glycans to mature, sialic acid-containing forms.
    1. Biochemistry and Chemical Biology

    Optical tools for visualizing and controlling human GLP-1 receptor activation with high spatiotemporal resolution

    Loïc Duffet, Elyse T Williams ... Tommaso Patriarchi
    A genetically encoded sensor and a photocaged peptide together enable precise investigation of human glucagon-like peptide-1 receptor activation with high spatiotemporal resolution.
    1. Neuroscience

    Dynamic behavior of the locus coeruleus during arousal-related memory processing in a multi-modal 7T fMRI paradigm

    Heidi IL Jacobs, Nikos Priovoulos ... Kâmil Uludağ
    By combining ultra-high-field imaging with physiological and saliva measures it is established that interactions between locus coeruleus, hippocampus and amygdala vary along emotional memory stages, putatively reflecting distinct cognitive states.
    1. Neuroscience

    Orbital frontal cortex updates state-induced value change for decision-making

    Emily T Baltz, Ege A Yalcinbas ... Christina M Gremel
    Orbital frontal cortex projection neuron activity is necessary to update state-dependent value change to control model-based behavior.

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