723 results found
    1. Developmental Biology
    2. Medicine

    RAB23 coordinates early osteogenesis by repressing FGF10-pERK1/2 and GLI1

    Md Rakibul Hasan, Maarit Takatalo ... David PC Rice
    RAB23 regulates calvarial bone and suture development both independently through, and by cross-talk between, Hedgehog and fibroblast growth factor signaling.
    1. Neuroscience

    The cerebellum is involved in processing of predictions and prediction errors in a fear conditioning paradigm

    Thomas Michael Ernst, Anna Evelina Brol ... Dagmar Timmann
    Pronounced cerebellar activation during unexpected omission of a potentially harmful event suggests that the cerebellum has to be added to the neural network processing prediction errors underlying emotional associative learning.
    1. Neuroscience

    Frequency-specific cortico-subcortical interaction in continuous speaking and listening

    Omid Abbasi, Nadine Steingräber ... Joachim Gross
    Distinct frequency-based interactions between cortical and subcortical regions highlight the cerebellum’s crucial role in speech production and perception.
    Version of Record
    Short Report
    • Valuable
    • Incomplete
    1. Neuroscience

    Instructed knowledge shapes feedback-driven aversive learning in striatum and orbitofrontal cortex, but not the amygdala

    Lauren Y Atlas, Bradley B Doll ... Elizabeth A Phelps
    While the striatum and orbitofrontal cortex learn about threats through verbal warnings, the amygdala learns only from direct experience, suggesting that the amygdala forms part of a specialized threat detection system.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics

    Ziva Vuckovic, Jinan Wang ... David M Thal
    Structural biology studies reveal the importance of protein dynamics on understanding molecular mechanisms underlying allosteric modulation of G protein-coupled receptors (GPCR) that offer insights into future GPCR research and drug discovery.
    1. Neuroscience

    Medical education and distrust modulate the response of insular-cingulate network and ventral striatum in pain diagnosis

    Giada Dirupo, Sabrina Totaro ... Corrado Corradi-Dell'Acqua
    Behavioral and neural data converge in showing that medical experience reduces reactions to others' pain and distrust toward the target affects the processing of his feedback.
    1. Neuroscience

    Neural mechanisms of credit assignment for delayed outcomes during contingent learning

    Phillip P Witkowski, Lindsay Rondot ... Erie D Boorman
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Neuroscience

    Changes in large-scale neural networks under stress are linked to affective reactivity to stress in real life

    Rayyan Tutunji, Martin Krentz ... Erno J Hermans
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience

    Thalamocortical contributions to cognitive task activity

    Kai Hwang, James M Shine ... Evan Sorenson
    Human thalamic activity transformed via thalamocortical functional connectivity to support task representations across functional domains.
    1. Neuroscience

    How adverse childhood experiences get under the skin: A systematic review, integration and methodological discussion on threat and reward learning mechanisms

    Julia Ruge, Mana R Ehlers ... Tina B Lonsdorf
    Individuals with a history of adverse childhood experiences show blunted response to threat and reward irrespective of sample and paradigm characteristics and despite heterogeneity in adversity operationalization and assessment.

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