Visualization and quantitative analyses of calcium ion oscillations in the endothelial cells of zebrafish embryos reveal how vascular endothelial growth factor (VEGF) and Dll4/Notch signaling regulate sprouting angiogenesis.
Tgfbr1 signaling governs all processes associated with the trunk to tail transition, including the repositioning of neuro-mesodermal progenitors, as well as the remodeling of the lateral plate mesoderm and embryonic endoderm.
Emergence of hematopoietic stem cells from an aortic component is a unique phenomenon of cell extrusion, with no equivalent in cell biology, and which is adapted to environmental constraints exerted by endothelial cells and hemodynamics forces.
Single-cell RNA sequencing analysis of diabetic mouse cavernous tissue revealed that LBH is a novel pericyte marker and may interact with Crystallin Alpha B and Vimentin to promote neurovascular regeneration.
Ryota L Matsuoka, Michele Marass ... Didier YR Stainier
Identification of a novel role for central nervous system-resident progenitors in the patterning of the vascular network around the developing spinal cord.
Denise M Poltavski, Pauline Colombier ... Takako Makita
Second-order guidance, a novel mechanism by which an initial guidance cue controls expression of a second guidance receptor, is required for precise refinement of axon trajectories during PNS development.
The transcription factor GATA6 selects the embryonic vessels that will be reorganized into the major thoracic arteries by promoting local differentiation of vascular smooth muscle cells.
Marina Venero Galanternik, Daniel Castranova ... Brant M Weinstein
A new brain perivascular cell type in the zebrafish related to mammalian Fluorescent Granular Perithelial (FGP) cells emerges directly from endothelium during early development.
