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    1. Neuroscience

    Coupling of pupil- and neuronal population dynamics reveals diverse influences of arousal on cortical processing

    Thomas Pfeffer, Christian Keitel ... Joachim Gross
    Spontaneous fluctuations in pupil-indexed arousal shape human cortical dynamics in a frequency-dependent and spatially diverse manner.
    1. Neuroscience

    Population receptive fields in nonhuman primates from whole-brain fMRI and large-scale neurophysiology in visual cortex

    P Christiaan Klink, Xing Chen ... Pieter R Roelfsema
    Within-species comparison of population receptive fields determined with fMRI and electrophysiology in nonhuman primates reveals the neuronal basis of blood-oxygen-level-dependent-based retinotopy.
    1. Developmental Biology

    A scalable and tunable platform for functional interrogation of peptide hormones in fish

    Eitan Moses, Roman Franek, Itamar Harel
    A novel in vivo strategy for reversible, multiplexed control of circulating hormone expression levels, achieved by combining genome-editing and intramuscular electroporation of fluorescently tagged hormones in the naturally short-lived turquoise killifish.
    1. Developmental Biology
    2. Neuroscience

    Maturation of Purkinje cell firing properties relies on neurogenesis of excitatory neurons

    Meike E van der Heijden, Elizabeth P Lackey ... Roy V Sillitoe
    Intersectional genetics show that excitatory neurons are essential for the functional and anatomical maturation of cerebellar circuits in mice.
    1. Physics of Living Systems

    Arnold tongue entrainment reveals dynamical principles of the embryonic segmentation clock

    Paul Gerald Layague Sanchez, Victoria Mochulska ... Alexander Aulehla
    A microfluidic experimental approach combined with dynamical systems theory reveals how to entrain an embryonic oscillator, the segmentation clock, and allows for the quantification of its entrainment properties.
    1. Cancer Biology
    2. Cell Biology

    Bestrophin-4 relays HES4 and interacts with TWIST1 to suppress epithelial-to-mesenchymal transition in colorectal cancer cells

    Zijing Wang, Bihan Xia ... Jilin Yang
    The inhibition of colorectal cancer (CRC) proliferation, migration, and invasion is attributed to BEST4, which exhibits epistasis over Hes4 in the downregulation of Twist1 and consequent suppression of epithelial-to-mesenchymal transition in CRC.
    1. Neuroscience

    The role of anterior insular cortex inputs to dorsolateral striatum in binge alcohol drinking

    David L Haggerty, Braulio Munoz ... Brady K Atwood
    A novel brain circuit that determines how much alcohol a mouse binge drinks by complex control of drinking behavior mechanics is surveyed.
    1. Developmental Biology
    2. Neuroscience

    Lifelong regeneration of cerebellar Purkinje cells after induced cell ablation in zebrafish

    Sol Pose-Méndez, Paul Schramm ... Reinhard W Köster
    Purkinje cell-specific ablation demonstrates regeneration of these neurons and functional recovery of the cerebellum during both larval and adult zebrafish.
    1. Neuroscience

    Cerebellar Purkinje Cells Control Posture in Larval Zebrafish (Danio rerio)

    Franziska Auer, Katherine Nardone ... David Schoppik
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Hippocampus and striatum show distinct contributions to longitudinal changes in value-based learning in middle childhood

    Johannes Falck, Lei Zhang ... Yee Lee Shing
    Longitudinal and computational analyses reveal an early and temporally stable hippocampal and striatal involvement in reinforcement learning in 6-to-7-year-old children.