The gustatory receptor PxylGr34 is tuned to the steroid plant hormone brassinolide and mediates the deterrent effects of brassinolide on feeding and ovipositing behaviors in Plutella xylostella.

Experiments using zebrafish identify a novel sleep-promoting neuronal circuit in which hypothalamic NPVF neurons promote sleep via the hindbrain serotonergic raphe nuclei, which promote sleep in both zebrafish and mice.

A novel class of bacterial OTU deubiquitinases provides insights on the distinct roles of bacterial deubiquitinases in host–pathogen interactions.

Poxin enzymes are a diverse family of insect and viral 2′3′-cGAMP nucleases, which evolved from self-cleaving RNA virus accessory proteases.

A photoswitchable pore blocker was covalently attached to a cysteine-substituted glutamate delta 2 receptor, to provide optical control of its ion channel function.

Knockout of Snord115 has mild impact on expression and function of the serotonin 2C receptor.

A novel bacterial deubiquitinase with multiple chain types specificity regulates the association of ubiquitinated proteins on the phagosome of Legionella pneumophila.

Ser57 phosphorylation of ubiquitin protects the cell during proteotoxic stress.

Experience strengthens hunting in larval zebrafish by recruiting the forebrain to increase the prey-evoked activity in visual areas and trigger motor activity and prey capture.

High-resolution maps and models of the bacterial ribosome provide new chemical insights into protein synthesis, and should enable the development of robust tools for cryo-EM structure modeling and refinement.