Dorsomedial and dorsolateral striatal neural activity differ during early learning of action sequences but do not change with performance improvement across sessions, and become similar after extended training.

During a spatial working memory task, neurons in the dorsomedial striatum encode the sample stimulus most strongly towards the onset of the delay period, while they display sequential firing activity that more evenly spans the delay period.

The structural characteristics of a circuit and its hierarchical dimensions are shown to influence regional time-series dynamics after targeted cellular-level manipulations.

Direct and indirect pathway neurons in posterior dorsomedial striatum were found to play distinct roles, with the former necessary for encoding and the latter for updating goal-directed learning.

The first comprehensive map of all excitatory inputs to the mouse striatum is presented and used to define and demarcate striatal subdivisions, including a previous unappreciated novel subdivision in the posterior striatum.

Dorsomedial D2-MSNs and D1-MSNs exhibit opposing dynamics during interval timing, however disrupting either MSN type produces similar effects on behavior, highlighting the complementary roles of striatal pathways in cognitive operations.

Analysis of slow wave brain state unravels the functional connectivity and the biological substrate of the rodent dorsolateral and dorsomedial striatum, demonstrating its organization in two non-overlapping circuits.

A novel connection from ventral striatum to motor cortex enables emotion and motivation to influence action and motor control.

Dopamine signals in the ventral, dorsomedial, and dorsolateral striatum are modulated by various variables, such as stimulus-associated value, choice, confidence, but these modulations can be inclusively explained by TD errors.

Neurons in the rat striatum respond preferentially to long or short time intervals, enabling the animal to track the passage of time.