Browse the search results

Global analyses using aneuploid Drosophila revealed the dynamic roles of RNA m⁶A modification in regulating gene expression and development under genomic imbalance, highlighting its potential relationships with dosage-related effects.

Fully functional regulatory elements can arise rapidly from transposable elements via a novel route where non-allelic gene conversion can act to speed up the evolutionary fine-tuning of regulatory elements.

Loading and linear translocation of condensin dosage compensation along the X-chromosomes create the loop-anchored topologically associating domains detected by Hi-C.

ChAR-seq is a massively parallelized de novo RNA mapping assay, which is capable of generating hundreds to thousands of RNA-binding maps with no a priori knowledge of target RNAs.

By properly accounting for gene copy number and cell-cycle effects, single cell snapshots of nascent and mature mRNA can be used to unveil the stochastic kinetics of gene activity.

Combining computational and experimental approaches reveals that the loss of a maternal transcription factor influences sex-biased differential splicing in the early zygotic transcriptome at genes that are critical for normal developmental processes.

A long noncoding RNA uses viral mimicry to achieve developmental gene silencing across a chromosome.

Maternal CLAMP functions as a novel pioneer transcription factor to open chromatin and plays a targeted yet essential role in Drosophila zygotic genome activation.

Analyses of allelic- and socially-biased gene expression reveal that suppressed recombination causes most of the expression differences in the social supergene, with only few differences due to socially antagonistic selection.