1,518 results found
    1. Developmental Biology

    Germ cell connectivity enhances cell death in response to DNA damage in the Drosophila testis

    Kevin L Lu, Yukiko M Yamashita
    Genetic and cell biological study indicates that germ cells' connectivity serves as a mechanism to increase the sensitivity of germline to DNA damage, protecting the genome of gametes, in the Drosophila testis.
    1. Genetics and Genomics

    Determining the genetic basis of anthracycline-cardiotoxicity by molecular response QTL mapping in induced cardiomyocytes

    David A Knowles et al.
    Genetic variants that modulate transcriptomic response to doxorubicin in human iPSC-derived cardiomyocytes are predictive of cardiac damage and in vivo sensitivity to anthracycline cardiotoxicity.
    1. Neuroscience

    Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau

    Maxime WC Rousseaux et al.
    Loss of a developmentally essential gene in adulthood is tolerated in mice, thus offering potential therapeutic options for Alzheimer's and Parkinson's disease.
    1. Human Biology and Medicine

    Stem Cells: Put to the test

    Marites T Woon, Timothy J Kamp
    Personalized heart muscle cells made from stem cells in the laboratory could be used to check an individual’s response to potential new drugs before clinical trials.
    Insight
    Available as:
    • HTML
    • PDF
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Bacterial Evolution: The road to resistance

    Devon M Fitzgerald
    The way that bacteria grow—either floating in liquid or attached to a surface—affects their ability to evolve antimicrobial resistance and our ability to treat infections.
    Insight
    Available as:
    • HTML
    • PDF
  1. Point of View: Unbridle biomedical research from the laboratory cage

    Garet P Lahvis
    Recent advances in technology now make it possible to carry out biomedical research on animals living in the wild, or captive animals living in naturalistic conditions.
    1. Neuroscience

    Olfaction: Catching more flies with vinegar

    Genevieve C Jouandet, Marco Gallio
    Insight
    Available as:
    • HTML
    • PDF
    1. Biochemistry and Chemical Biology
    2. Human Biology and Medicine

    Cancer: How does doxorubicin work?

    Anand G Patel, Scott H Kaufmann
    Insight
    Available as:
    • HTML
    • PDF
    1. Human Biology and Medicine
    2. Neuroscience

    Point of View: Predictive regulation and human design

    Peter Sterling
    Why does the human regulatory system, which evolution tuned for small satisfactions, now constantly demand 'more'?
    1. Cell Biology
    2. Computational and Systems Biology

    Science Forum: The Human Cell Atlas

    Aviv Regev et al.
    Advances in techniques for analysing single cells and tissues have inspired an international effort to create comprehensive reference maps of all human cells - the fundamental units of life - as a basis for both understanding human health and diagnosing, monitoring and treating disease.

Refine your results by:

Type
Research categories