1,098 results found
    1. Neuroscience

    Sources of noise during accumulation of evidence in unrestrained and voluntarily head-restrained rats

    Benjamin B Scott et al.
    Statistical analysis of evidence-based decisions reveals new insights into the source of behavioral variability.
    1. Neuroscience

    Behavioral evidence for memory replay of video episodes in the macaque

    Shuzhen Zuo et al.
    Macaque monkeys temporally compress past experiences and use a forward-replay mechanism during judgment of temporal-order between episodes.
    1. Neuroscience

    Cognitive regulation alters social and dietary choice by changing attribute representations in domain-general and domain-specific brain circuits

    Anita Tusche, Cendri A Hutcherson
    Regulatory success operates by goal-consistent increases and decreases of distinct attribute representations in generic neural hubs and in domain-specific brain regions, explaining when and why regulatory success generalizes across domains and contexts.
    1. Neuroscience

    Maximally informative foraging by Caenorhabditis elegans

    Adam J Calhoun et al.
    C. elegans foraging efficiently approximate maximally informative search strategies that involve abrupt switching between different types of behaviors.
    1. Neuroscience

    Normative evidence accumulation in unpredictable environments

    Christopher M Glaze et al.
    Theoretically optimal dynamics for making decisions in unpredictable environments provide a broadly applicable framework for understanding choice behavior and underlying neural signals.
    1. Neuroscience

    Decision Making: Remembering to choose the future

    Lesley K Fellows
    A brain region known as the hippocampus is required when people assess different options before making a value-based choice.
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    1. Cell Biology

    The step-wise pathway of septin hetero-octamer assembly in budding yeast

    Andrew Weems, Michael McMurray
    In budding yeast cells, slow monomeric septin GTPase activity and the cytosolic GTP:GDP ratio dictate the relative incorporation of alternative subunits during septin hetero-oligomer assembly, which proceeds by discrete, ordered steps dependent on allostery between interaction interfaces.
    1. Neuroscience

    Distinct mechanisms mediate speed-accuracy adjustments in cortico-subthalamic networks

    Damian M Herz et al.
    Dynamic changes in activity and connectivity of the human subthalamic nucleus reflect whether a decision will be made in haste or with caution.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Membrane insertion of α-xenorhabdolysin in near-atomic detail

    Evelyn Schubert et al.
    Cryo-EM and X-ray structures of α-xenorhabdolysin in soluble and pore form of Xenorhabdus nematophila give novel insights into the mechanism of action of bi-component α-pore-forming toxins.

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