Combining powerful simulation methods uncovers the structural and dynamical changes driving G protein activation in atomic detail, revealing the allosteric network that triggers GDP release and reconciling diverse experimental data.

Virtual reality experiments show that motorists slow down when driving in fog, but they speed up when visibility is reduced equally at all distances.

Human Neocortical Neurosolver is a new user-friendly software tool for researchers to develop and test hypotheses on cellular/circuit origins of human MEG/EEG signals using a biophysical model.

A computer model of human cardiomyocyte was produced and validated on independent datasets, overcoming shortcomings of its predecessors, also yielding broadly relevant insights and results on major ionic currents.

On entry to meiosis, chromosomes scattered in the large oocyte nucleus of starfish are collected by an F-actin network, which contracts by an unexpected, myosin-independent mechanism based on local assembly and global disassembly of actin filaments.

Driving theta–gamma activity in the human cortex with non-invasive brain stimulation enhances motor skill acquisition in healthy adults, revealing a potential neuroplastic mechanism that might be harnessed for therapeutic intervention.

Mathematical models with experimental validation show that chloride transporters in the cell membrane, and not negatively charged impermeant molecules, generate the driving force used by GABA receptors to silence neurons.

Cholinergic system play an important role in waking-to-sleep cycles and in sleep stabilization.

A general mechanism for how powerful forces of assembly and protein mobility can emerge from phase transitions is established.