Browse the search results

Page 2 of 459
    1. Neuroscience

    Long-term consequences of the absence of leptin signaling in early life

    Angela M Ramos-Lobo, Pryscila DS Teixeira ... Jose Donato Jr
    A mouse model that grew without functional leptin receptors until adulthood reveals that early defects in leptin signaling lead to permanent metabolic and developmental problems.
    1. Evolutionary Biology

    Transition to siblinghood causes a substantial and long-lasting increase in urinary cortisol levels in wild bonobos

    Verena Behringer, Andreas Berghänel ... Gottfried Hohmann
    In wild bonobos, sibling birth induced a sudden increase in urinary cortisol levels in the older offspring, a physiological response that occurred in all subjects and was independent of their age.
    1. Ecology
    2. Evolutionary Biology

    Social groups buffer maternal loss in mountain gorillas

    Robin E Morrison, Winnie Eckardt ... Tara S Stoinski
    In mountain gorillas, as in certain human populations, relationships between group members can act as a social buffer, breaking the link between maternal loss, increased social adversity, and decreased fitness.
    1. Neuroscience

    Compensation for PKMζ in long-term potentiation and spatial long-term memory in mutant mice

    Panayiotis Tsokas, Changchi Hsieh ... Todd Charlton Sacktor
    The enzyme PKMzeta is crucial for the maintenance of long-term memories, but a closely related enzyme provides a back-up should PKMzeta fail, thus explaining the controversy over why deleting the gene for PKMzeta may not appear to impair memory.
    1. Neuroscience

    Language experience shapes predictive coding of rhythmic sound sequences

    Piermatteo Morucci, Sanjeev Nara ... Nicola Molinaro
    A magnetoencephalography study across different languages shows that life-long listening experience influences the neural mechanisms underlying rhythm perception.
  1. Research Culture: Virtual conferences raise standards for accessibility and interactions

    Sarvenaz Sarabipour
    Virtual conferences benefit the scientific community by increasing the number and diversity of attendees compared to in-person conferences, and by being less time consuming, more economic and environmentally friendly.
    1. Immunology and Inflammation

    The anti-caspase 1 inhibitor VX-765 reduces immune activation, CD4+ T cell depletion, viral load, and total HIV-1 DNA in HIV-1 infected humanized mice

    Mathieu Amand, Philipp Adams ... Carole Seguin-Devaux
    Inflamasomme inhibition prevents immune activation, HIV-1 pathogenesis and the splenic content of HIV-1 total DNA in humanized mice when administrated early after HIV-1 infection.
    1. Cancer Biology
    2. Developmental Biology

    Neural stem cell-encoded temporal patterning delineates an early window of malignant susceptibility in Drosophila

    Karine Narbonne-Reveau, Elodie Lanet ... Cédric Maurange
    Sequentially expressed temporal transcription factors in neural stem cells during early development determine which progeny can undergo malignant transformation upon dedifferentiation.
    1. Neuroscience

    LTD at amygdalocortical synapses as a novel mechanism for hedonic learning

    Melissa S Haley, Stephen Bruno ... Arianna Maffei
    Taking advantage of awell-established learning paradigm, conditioned taste aversion (CTA), change of hedonic value of a palatable tastant revealed the neural mechanisms encoding this learning process.
    1. Evolutionary Biology

    Adaptation dynamics between copy-number and point mutations

    Isabella Tomanek, Călin C Guet
    In bacteria, frequent adaptive copy-number mutations can hinder the fixation of beneficial point mutations and hence the divergence of duplicated DNA sequences.