This sesquiterpene hormone likely acted as a morphogenesis-to-differentiation switch in archaic embryos before it evolved its postembryonic function as the status quo regulator of insect metamorphosis.

Understanding novel cell types and their evolutionary history is re-evaluated using single nuclei transcriptomic approaches and their inferred underlying gene regulatory networks.

A single-cell atlas of the adult fly VNC charts the types and properties of cells for future studies of brain development and function.

A meta-analysis yields a spatiotemporal map of gene expression that provides a blueprint for nematode cuticle construction and reveals novel families of cuticular intrinsically disordered proteins.

The sweet taste receptors in the cotton bollworm (Helicoverpa armigera) are evolved to adapt towards the larval and adult foods with different types and amounts of sugar.

Belly roll, Bero, an Ly6/α-neurotoxin family protein, is identified as a critical modulator of peptidergic interneurons in Drosophila melanogaster, shedding light on genetic regulations of nociceptive escape behaviors and providing a potential target for future studies on pain perception.

Single-nuclear transcriptomic profiling and functional assays identified PKR activation and mitochondrial dysfunction in HIV-associated nephropathy mice kidneys.