24 results found
    1. Developmental Biology
    2. Evolutionary Biology

    Functional divergence of paralogous transcription factors supported the evolution of biomineralization in echinoderms

    Jian Ming Khor, Charles A Ettensohn
    A gene duplication event has permitted the functional specialization of a homeodomain transcription factor through changes in exon-intron organization and these changes have supported the evolution of a major, phylum-level morphological novelty.
    1. Developmental Biology
    2. Evolutionary Biology

    Logics and properties of a genetic regulatory program that drives embryonic muscle development in an echinoderm

    Carmen Andrikou et al.
    A gene regulatory network model provides a simplified explanation of the molecular interactions that orchestrate muscle development in the sea urchin embryo.
    1. Immunology and Inflammation

    Cytokines: A gut response

    Matthew L Nicotra
    Unexpected findings from the immune system of sea urchin larvae potentially provide insights into immune signaling in ancestral lifeforms.
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    1. Immunology and Inflammation

    IL17 factors are early regulators in the gut epithelium during inflammatory response to Vibrio in the sea urchin larva

    Katherine M Buckley et al.
    Expression of two highly regulated subfamilies of the complex multigene family encoding IL-17 cytokines in the purple sea urchin are sequentially activated in a larval gut-associated inflammation model and modulate downstream gene expression in the gut epithelium.
    1. Genetics and Genomics
    2. Neuroscience

    Evolution: The enigmatic xenopsins

    Detlev Arendt
    A new member of the family of light-sensitive proteins called opsins has stirred up our view of photoreceptors.
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    1. Developmental Biology
    2. Evolutionary Biology

    Development: Transforming a transcription factor

    Robert D Burke
    A transcription factor that regulates skeleton formation in sea urchin embryos has evolved a new domain that is essential for this process.
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    1. Developmental Biology
    2. Genetics and Genomics

    The genome of the crustacean Parhyale hawaiensis, a model for animal development, regeneration, immunity and lignocellulose digestion

    Damian Kao et al.
    The first malacostracan genome sequence will establish the genetically tractable Parhyale hawaiensis as a model organism in this key animal group.
    1. Stem Cells and Regenerative Medicine

    Distinct mechanisms underlie oral vs aboral regeneration in the cnidarian Hydractinia echinata

    Brian Bradshaw et al.
    Stem cell migration underlies head regeneration in the cnidarian (jellies and their kin) Hydractinia, but the regeneration of other body parts is based on the gradual transformation of one tissue type into another.
    1. Developmental Biology
    2. Evolutionary Biology

    CRISPR knockouts reveal an endogenous role for ancient neuropeptides in regulating developmental timing in a sea anemone

    Nagayasu Nakanishi, Mark Q Martindale
    Analysis of the endogenous function of deeply conserved neuropeptides in sea anemones sheds light on a primitive role of nervous systems in modulating developmental timing.
    1. Genetics and Genomics
    2. Neuroscience

    Co-expression of xenopsin and rhabdomeric opsin in photoreceptors bearing microvilli and cilia

    Oliver Vöcking et al.
    The recently characterized opsin group of xenopsins is likely a major player in animal eye evolution and may have been present in an ancient, highly plastic eye photoreceptor cell type.

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