74 results found
    1. Developmental Biology
    2. Genetics and Genomics

    The genome sequence of the colonial chordate, Botryllus schlosseri

    Ayelet Voskoboynik, Norma F Neff ... Stephen R Quake
    The Botryllus schlosseri genome yields insights into the evolution of hematopoiesis.
    1. Cell Biology
    2. Neuroscience

    PTRN-1, a microtubule minus end-binding CAMSAP homolog, promotes microtubule function in Caenorhabditis elegans neurons

    Claire E Richardson, Kerri A Spilker ... Kang Shen
    The protein PTRN-1 anchors microtubules in neuronal branches to promote proper neuron morphology and function in Caenorhabditis elegans.
    1. Stem Cells and Regenerative Medicine

    Distinct mechanisms underlie oral vs aboral regeneration in the cnidarian Hydractinia echinata

    Brian Bradshaw, Kerry Thompson, Uri Frank
    Stem cell migration underlies head regeneration in the cnidarian (jellies and their kin) Hydractinia, but the regeneration of other body parts is based on the gradual transformation of one tissue type into another.
    1. Developmental Biology
    2. Evolutionary Biology

    Logics and properties of a genetic regulatory program that drives embryonic muscle development in an echinoderm

    Carmen Andrikou, Chih-Yu Pai ... Maria Ina Arnone
    A gene regulatory network model provides a simplified explanation of the molecular interactions that orchestrate muscle development in the sea urchin embryo.
    1. Developmental Biology
    2. Genetics and Genomics

    The genome of the crustacean Parhyale hawaiensis, a model for animal development, regeneration, immunity and lignocellulose digestion

    Damian Kao, Alvina G Lai ... Aziz Aboobaker
    The first malacostracan genome sequence will establish the genetically tractable Parhyale hawaiensis as a model organism in this key animal group.
    1. Neuroscience

    The CNS connectome of a tadpole larva of Ciona intestinalis (L.) highlights sidedness in the brain of a chordate sibling

    Kerrianne Ryan, Zhiyuan Lu, Ian A Meinertzhagen
    Serial-section EM analysis uncovers the CNS connectome of a Ciona larva, the second of any entire nervous system, and exposes left-right asymmetries in its synaptic circuits.
    1. Developmental Biology
    2. Evolutionary Biology

    The evolutionary origin of bilaterian smooth and striated myocytes

    Thibaut Brunet, Antje HL Fischer ... Detlev Arendt
    Molecular profiling of annelid myocytes reveals that the last common protostome-deuterostome ancestor already possessed a dual musculature, with visceral smooth muscles ensuring digestion and somatic striated muscles ensuring locomotion.
    1. Immunology and Inflammation

    Cytokines: A gut response

    Matthew L Nicotra
    Unexpected findings from the immune system of sea urchin larvae potentially provide insights into immune signaling in ancestral lifeforms.
    Version of Record
    Insight
    1. Immunology and Inflammation

    IL17 factors are early regulators in the gut epithelium during inflammatory response to Vibrio in the sea urchin larva

    Katherine M Buckley, Eric Chun Hei Ho ... Jonathan P Rast
    Expression of two highly regulated subfamilies of the complex multigene family encoding IL-17 cytokines in the purple sea urchin are sequentially activated in a larval gut-associated inflammation model and modulate downstream gene expression in the gut epithelium.
    1. Neuroscience

    Ciliomotor circuitry underlying whole-body coordination of ciliary activity in the Platynereis larva

    Csaba Verasztó, Nobuo Ueda ... Gáspár Jékely
    Connectomic reconstruction combined with activity imaging uncovered a rhythmically active neuronal circuit for the coordination of ciliary activity across the whole body of a marine larva.

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