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    1. Evolutionary Biology

    Dynamic simulations of feeding and respiration of the early Cambrian periderm-bearing cnidarian polyps

    Yiheng Zhang, Xing Wang ... Xiaoguang Yang
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Solid
    1. Evolutionary Biology
    2. Genetics and Genomics

    Expansion and loss of sperm nuclear basic protein genes in Drosophila correspond with genetic conflicts between sex chromosomes

    Ching-Ho Chang, Isabel Mejia Natividad, Harmit S Malik
    Genetic conflicts between sex chromosomes during spermatogenesis may drive the rapid evolution, function, and turnover of some sperm nuclear basic proteins in Drosophila species.
    1. Developmental Biology
    2. Evolutionary Biology

    Wnt/β-catenin signaling is an evolutionarily conserved determinant of chordate dorsal organizer

    Iryna Kozmikova, Zbynek Kozmik
    Wnt/beta-catenin signaling is essential for the specification of dorsal cell fate in amphioxus, suggesting a common evolutionary origin for the formation of the dorsal organizer in chordates.
    1. Neuroscience

    The CNS connectome of a tadpole larva of Ciona intestinalis (L.) highlights sidedness in the brain of a chordate sibling

    Kerrianne Ryan, Zhiyuan Lu, Ian A Meinertzhagen
    Serial-section EM analysis uncovers the CNS connectome of a Ciona larva, the second of any entire nervous system, and exposes left-right asymmetries in its synaptic circuits.
    1. Developmental Biology
    2. Genetics and Genomics

    The genome sequence of the colonial chordate, Botryllus schlosseri

    Ayelet Voskoboynik, Norma F Neff ... Stephen R Quake
    The Botryllus schlosseri genome yields insights into the evolution of hematopoiesis.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Hypoxia triggers collective aerotactic migration in Dictyostelium discoideum

    Olivier Cochet-Escartin, Mete Demircigil ... Jean-Paul Rieu
    Cell assemblies can use environmental cues created by their own respiration, such as oxygen gradients, to collectively guide themselves to more favorable locations in a remarkably robust and long-lasting way.
    1. Physics of Living Systems

    Sperm chemotaxis is driven by the slope of the chemoattractant concentration field

    Héctor Vicente Ramírez-Gómez, Vilma Jimenez Sabinina ... Adán Guerrero
    The slope of the chemoattractant concentration gradient is a driving force for sperm chemotaxis, by coordinating the entrainment of information flow between sensing, signaling and motility.
    1. Developmental Biology
    2. Evolutionary Biology

    Conservation of peripheral nervous system formation mechanisms in divergent ascidian embryos

    Joshua F Coulcher, Agnès Roure ... Sébastien Darras
    Developmental regulatory mechanisms for peripheral nervous system formation appear to be conserved in ascidians despite extensive genomic divergence after 390 MY of separate evolution.
    1. Immunology and Inflammation
    2. Evolutionary Biology

    Evolutionary and functional analyses reveal a role for the RHIM in tuning RIPK3 activity across vertebrates

    Elizabeth J Fay, Kolya Isterabadi ... Matthew D Daugherty
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cell Biology
    2. Physics of Living Systems

    Co-movement of astral microtubules, organelles and F-actin by dynein and actomyosin forces in frog egg cytoplasm

    James F Pelletier, Christine M Field ... Timothy J Mitchison
    Live imaging of multiple cytoplasmic networks in frog egg extracts calls for new models for how egg cytoplasm is physically organized during cleavage divisions.