Whole genome sequencing of 19 populations of Atlantic and Baltic herring reveals hundreds of individual loci underlying adaptation to a low salinity niche or timing of reproduction.

Genome engineering and phenotyping in vivo reveal surprising new features of adaptive amino acid substitutions that were previously inaccessible.

Cell biological and genetic analyses reveal how budding yeast cells optimize Spindle Assembly checkpoint signaling to maximize chromosome segregation accuracy and minimize unnecessary delays in anaphase onset.

A comprehensive genetic interaction screen uncovered biological roles of K11 linkages in amino acid homeostasis and cell cycle regulation in yeast.

Structural and genetic analyses reveal the highly evolved and unprecedented biological strategy used by SaPIs to spread in nature.

Cell biological and genetic studies reveal age-associated alterations of lysosomes and modulation of lysosomal activity by longevity pathways.

Cell biological features are subject to stochastic forces of mutation and random genetic drift, which together cause lineages exposed to identical selection pressures to diverge, and mean phenotypes to deviate from expectations under optimizing selection.

Common nuclear genetic variants are associated with fundamental biological processes occurring in human mitochondria and potentially point to novel roles for nuclear genes in transcriptional regulation of the mitochondrial genome.

Genetic, biochemical, and cell biological approaches reveal a new form of contact-dependent inhibition in bacteria involving bacteriocin-like proteins that aggregate on the surface of cells.