123 results found
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    Evolutionary principles of modular gene regulation in yeasts

    Dawn A Thompson, Sushmita Roy ... Aviv Regev
    The divergence of gene regulation during evolution in yeast traces phylogenetic distance with prominent changes being associated with changes in lifestyle and a whole genome duplication event.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Global distribution maps of the leishmaniases

    David M Pigott, Samir Bhatt ... Simon I Hay
    Maps defining environmental risk of the leishmaniases provide insights into the ecology of these diseases and identify regions to target public health measures and inform future burden estimates.
    1. Ecology
    2. Microbiology and Infectious Disease

    Ecology and evolution of viruses infecting uncultivated SUP05 bacteria as revealed by single-cell- and meta-genomics

    Simon Roux, Alyse K Hawley ... Matthew B Sullivan
    Single-cell amplified genome sequencing uncovers virus-host interactions in uncultivated sulfur-oxidizing bacteria with relevance to coupled biogeochemical cycling in marine oxygen minimum zones.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Mapping the zoonotic niche of Ebola virus disease in Africa

    David M Pigott, Nick Golding ... Simon I Hay
    Understanding where future Ebola virus outbreaks may start and the changing nature of the populations living in these places is of critical importance in helping to prepare for future outbreaks.
    1. Evolutionary Biology

    Antibacterial gene transfer across the tree of life

    Jason A Metcalf, Lisa J Funkhouser-Jones ... Seth R Bordenstein
    Parallel horizontal gene transfer has spread a bacteriolytic gene family to all domains of life, and has bestowed a niche-transcending adaptation in recipients that must deploy antibacterial molecules to survive in a bacterial world.
    1. Ecology
    2. Epidemiology and Global Health

    The global distribution of the arbovirus vectors Aedes aegypti and Ae. albopictus

    Moritz UG Kraemer, Marianne E Sinka ... Simon I Hay
    The limits to the global distribution of the mosquitoes that transmit dengue and chikungunya have been predicted using a species distribution modelling approach.
    1. Computational and Systems Biology

    Calibration and analysis of genome-based models for microbial ecology

    Stilianos Louca, Michael Doebeli
    A novel computation tool for microbial community modeling predicts the evolution and diversification of E. coli in laboratory evolution experiments and gives insight into the underlying metabolic processes.
    1. Epidemiology and Global Health

    The effects of a deleterious mutation load on patterns of influenza A/H3N2's antigenic evolution in humans

    Katia Koelle, David A Rasmussen
    Deleterious mutations slow down flu's antigenic evolution, make it more punctuated in nature, and reduce the virus's genetic diversity.
    1. Biochemistry and Chemical Biology
    2. Evolutionary Biology

    Non-classical amine recognition evolved in a large clade of olfactory receptors

    Qian Li, Yaw Tachie-Baffour ... Stephen D Liberles
    Fish trace amine-associated receptors evolved a novel structural motif that enables the detection of chemically diverse amine odors in a non-canonical 'inverted' orientation.
    1. Evolutionary Biology

    Fine-tuning citrate synthase flux potentiates and refines metabolic innovation in the Lenski evolution experiment

    Erik M Quandt, Jimmy Gollihar ... Jeffrey E Barrick
    A long-term evolution experiment with Escherichia coli shows that the appearance and optimization of a new trait can require both co-opting existing cellular pathways for new roles and reversing a history of previous adaptation.

Refine your results by:

Type
Research categories