Disposal of ciliary proteins via ectosomes budding from cilia tip or cilia base acts as a safeguard mechanism when cilia trafficking functions are impaired.
The endosomal apparatus of African trypanosomes consists a continuous membrane system with functional subdomains rather than distinct compartments for early, late, and recycling endosomes.
Javier Ruiz-Navarro, Sara Fernández-Hermira ... Manuel Izquierdo Pastor
FMNL1β is phosphorylated on S1086 in a protein kinase C δ (PKCδ)-dependent manner and S1086-phosphorylated FMNL1β acts downstream of PKCδ to regulate centrosome and multivesicular bodies polarization to the immunological synapse and exosome release.
Sharon Elliot, Paola Catanuto ... Marilyn K Glassberg
A systemic feature of idiopathic pulmonary fibrosis whereby urine-derived exosomes contain pro-fibrotic microRNAs and interfere with response to tissue injury.
Cells package active receptors in endosomes at fairly constant amounts and can determine different cell-fate decisions by regulating the number and lifetime of receptor packages.