2,852 results found
    1. Neuroscience

    Neurophysiological evidence of efference copies to inner speech

    Thomas J Whitford et al.
    The silent production of words in one's mind generates an efference copy that is similar in nature to the efference copy associated with overt vocalization.
    1. Immunology and Inflammation
    2. Physics of Living Systems

    Quantitative modeling of the effect of antigen dosage on B-cell affinity distributions in maturating germinal centers

    Marco Molari et al.
    Detailed and inferred model reproduces B-cell affinity distributions measured in mice immunized according to various protocols and explains non-monotonous effects of antigen dosage on maturation.
    1. Neuroscience

    Neuronal representation of saccadic error in macaque posterior parietal cortex (PPC)

    Yang Zhou et al.
    Neurons in the macaque posterior parietal cortex behave like an error detector that computes the saccadic error by comparing the intended and the actual saccade end-position signals.
    1. Neuroscience

    A unified internal model theory to resolve the paradox of active versus passive self-motion sensation

    Jean Laurens, Dora E Angelaki
    Central vestibular regions in the brainstem and cerebellum perform dynamic Bayesian inference to combine motor commands and sensory signals into an optimal estimate of self-motion.
    1. Computational and Systems Biology

    A network of epigenetic modifiers and DNA repair genes controls tissue-specific copy number alteration preference

    Dina Cramer et al.
    The genetic background of a cancer cell and the chromatin organization of the tissue-of-origin impact the amount, length and position of somatic copy number alterations in cancer.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    The origins and relatedness structure of mixed infections vary with local prevalence of P. falciparum malaria

    Sha Joe Zhu et al.
    Variation in the rate of mixed infections by malaria parasites and the relatedness structure among infecting strains reveals diversity in local epidemiological processes.
    1. Genetics and Genomics

    Identification of an emphysema-associated genetic variant near TGFB2 with regulatory effects in lung fibroblasts

    Margaret M Parker et al.
    A functional genetic variant, rs1690789, affects susceptibility to emphysema by altering TGFB2 expression in human lung fibroblasts.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Genome plasticity in Candida albicans is driven by long repeat sequences

    Robert T Todd et al.
    Previously uncharacterized long repeat sequences are associated with significant genome variation that can increase fitness and promote antifungal drug resistance in diverse isolates of Candida albicans.
    1. Evolutionary Biology
    2. Plant Biology

    Natural selection and repeated patterns of molecular evolution following allopatric divergence

    Yibo Dong et al.
    The genomic architecture of allopatric species is a mosaic of many conserved genes and a few adaptive ones, reflecting balance between conservation of ancestral functions and evolution of new features.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    No current evidence for widespread dosage compensation in S. cerevisiae

    Eduardo M Torres et al.
    Dosage compensation does not take place in wild yeast strains.

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