404 results found
    1. Structural Biology and Molecular Biophysics

    Distinct gating mechanisms revealed by the structures of a multi-ligand gated K+ channel

    Chunguang Kong, Weizhong Zeng ... Youxing Jiang
    Structural and functional studies of a potassium ion channel that is opened and closed by different ligands have revealed a novel gating mechanism.
    1. Plant Biology
    2. Developmental Biology

    Sugar is an endogenous cue for juvenile-to-adult phase transition in plants

    Sha Yu, Li Cao ... Jia-Wei Wang
    Sugar levels in leaves act as a signal for plants to switch from their juvenile to their adult form by regulating the expression of two genes.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    MCU encodes the pore conducting mitochondrial calcium currents

    Dipayan Chaudhuri, Yasemin Sancak ... David E Clapham
    Genetic and electrophysiological experiments reveal that a gene called MCU encodes the ion channel pore that allows calcium ions to cross the inner mitochondrial membrane.
    1. Cell Biology

    Stapled Golgi cisternae remain in place as cargo passes through the stack

    Gregory Lavieu, Hong Zheng, James E Rothman
    The cisternae of the Golgi contain two functionally distinct domains: the central areas, which remain stationary, and the edges or rims, which are mobile.
    1. Plant Biology

    Temporal transcriptional response to ethylene gas drives growth hormone cross-regulation in Arabidopsis

    Katherine Noelani Chang, Shan Zhong ... Joseph R Ecker
    The plant hormone ethylene regulates the expression of multiple genes in the model plant Arabidopsis, including those that respond to other hormones.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    A family of fluoride-specific ion channels with dual-topology architecture

    Randy B Stockbridge, Janice L Robertson ... Christopher Miller
    Efflux of xenobiotic fluoride from microorganisms occurs through a novel family of ion channels with stringent selectivity for fluoride ion and dual-topology molecular architecture.
    1. Neuroscience

    Ultrafast endocytosis at Caenorhabditis elegans neuromuscular junctions

    Shigeki Watanabe, Qiang Liu ... Erik M Jorgensen
    Optogenetics has revealed that synaptic vesicles can be recycled extremely rapidly in nematodes, indicating that existing models for how synapses 'reload' may need to be revised.
    1. Biochemistry and Chemical Biology
    2. Ecology

    ABC transporter functions as a pacemaker for sequestration of plant glucosides in leaf beetles

    Anja S Strauss, Sven Peters ... Antje Burse
    A transport protein enables leaf beetle larvae to take up and store plant toxins and use them as part of their own defense strategy.
    1. Cell Biology
    2. Plant Biology

    Delivery of endocytosed proteins to the cell–division plane requires change of pathway from recycling to secretion

    Sandra Richter, Marika Kientz ... Gerd Jürgens
    The same membrane trafficking cargo can change pathways mediated by different members of ARF-GEF family of vesicle formation regulators.

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