2,800 results found
    1. Cancer Biology
    Reproducibility Project

    Reproducibility Project: Cancer Biology

    Curated by Roger Davis et al.
    Investigating reproducibility in preclinical cancer research.
  1. August 2015

    Episode 22: August 2015

    In this episode we hear about cancer, dengue fever, sperm DNA and neurons that are sensitive to magnetic fields.
  2. December 2013

    Episode 7: December 2013

    In this episode we hear about drug resistance, severe brain damage, sugar versus sweetener, public goods dilemmas, and the evolution of the machinary that makes proteins in cells.
  3. Episode 39: Spotlight on tropical diseases

    In this special episode we discuss diseases that are common in tropical countries including tuberculosis, Zika, malaria and schistosomiasis.
    1. Developmental Biology and Stem Cells

    Stem Cells: A Collection of Articles

    Curated by Sean Morrison
    eLife editors present a collection of stem cell research published in the journal.
    1. Neuroscience

    Chronic lithium treatment elicits its antimanic effects via BDNF-TrkB dependent synaptic downscaling

    Erinn S Gideons et al.
    The antimanic action of lithium requires BDNF-TrkB signaling coupled with enhanced dynamin-dependent endocytosis of AMPARs as a potential mechanism underlying the therapeutic effects.
    1. Cell Biology

    Cell cycle entry triggers a switch between two modes of Cdc42 activation during yeast polarization

    Kristen Witte et al.
    Optogenetic control of Cdc42 activation during polarization of budding yeast demonstrates a cell cycle regulated switch between two distinct modes of positive feedback.
    1. Computational and Systems Biology
    2. Neuroscience

    Saccadic suppression as a perceptual consequence of efficient sensorimotor estimation

    Frédéric Crevecoeur, Konrad P Kording
    Neural computations necessary for efficient control of saccades capture the phenomenon of saccadic suppression, which suggests that neural resources are shared for perception and control.
    1. Neuroscience

    Plasticity of calcium-permeable AMPA glutamate receptors in Pro-opiomelanocortin neurons

    Shigetomo Suyama et al.
    Neurons in the hypothalamus that promote satiety manifest plasticity of their response to the excitatory transmitter, glutamate, by re-organizing the composition of a specific glutamare receptor.
    1. Microbiology and Infectious Disease
    2. Neuroscience

    Microbiota regulates visceral pain in the mouse

    Pauline Luczynski et al.
    Determining that microbiota-deficient mice have increased visceral pain, which can be reversed by restoring microbiota, may lead to novel microbial-based strategies for disorders associated with visceral pain.

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