In this episode we hear about drug resistance, severe brain damage, sugar versus sweetener, public goods dilemmas, and the evolution of the machinary that makes proteins in cells.
MgADP binding to the high-affinity 'consensus' ATPase active site of SUR1 and remodeling of the L0-loop (lasso region) overrides tonic ATP inhibition of KATP channels.
Electrophysiological experiments, Ca2+ imaging, and behavioral studies in mice identify the TRPM3 ion channel as a novel target of G-protein βγ subunits.
Occluding-junctions form a permeability barrier around the hematopoietic niche in Drosophila that controls the production of immune cells in response to infection by shaping the signalling micro-environment produced by the niche.
The antibody accessibility of the leptospiral surface protein, LigB, provides a guide for the rational design of improved recombinant chimeric vaccine antigens displayed on a single domain scaffold.
The three main types of inhibitory neurons in mouse primary visual cortex respond differently to locomotion in darkness and during visual stimulation, revealing context-dependent responses to changes in behavioral state.
