2,799 results found
    1. Cell Biology
    2. Developmental Biology and Stem Cells

    Control of PNG kinase, a key regulator of mRNA translation, is coupled to meiosis completion at egg activation

    Masatoshi Hara et al.
    The kinase that controls maternal mRNA translation is regulated by phosphorylation of its activating subunit to restrict kinase activity to the developmental window between meiosis completion and early embryogenesis.
    1. Immunology and Inflammation

    The activation of IgM- or isotype-switched IgG- and IgE-BCR exhibits distinct mechanical force sensitivity and threshold

    Zhengpeng Wan et al.
    The B cell receptors of naïve B cells need higher levels of mechanical force to be fully activated than those of memory B cells.
    1. Neuroscience

    Activity of the C. elegans egg-laying behavior circuit is controlled by competing activation and feedback inhibition

    Kevin M Collins et al.
    The neural circuit that regulates egg-laying behavior in nematode worms is activated by egg production, coupled to the circuit that generates movement, and inhibited by sensory feedback from egg release.
    1. Neuroscience

    Food odors trigger Drosophila males to deposit a pheromone that guides aggregation and female oviposition decisions

    Chun-Chieh Lin et al.
    The activation of Drosophila Or7a receptors guides aggregation and egg-laying behaviors towards both green leaf volatiles and a male-specific food-odor-induced pheromone.
  1. Point of view: Motivating participation in open science by examining researcher incentives

    Sarah E Ali-Khan et al.
    A survey of researchers at the Montreal Neurological Institute and Hospital provides insights into the challenges and opportunities involved in adopting an open science policy across an entire patient-oriented academic institution.
    1. Cell Biology
    2. Neuroscience

    Hypoxia: Adapt or avoid

    Ganesh K Kumar
    Insight
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    1. Neuroscience

    Male Mating Behaviour: The importance of waiting

    Jarred Sanders, David Biron
    Insight
    Available as:
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    1. Microbiology and Infectious Disease

    Research: A comprehensive and quantitative exploration of thousands of viral genomes

    Gita Mahmoudabadi, Rob Phillips
    A compendium of critical genomic numbers for viruses through the lenses of different viral classification systems.
    1. Epidemiology and Global Health

    Science Forum: Unit of analysis issues in laboratory-based research

    Nick R Parsons et al.
    A simulation study is used to demonstrate how mistakes in identifying the experimental unit and the unit of analysis can lead to incorrect analyses and inappropriate inferences when reporting research studies.
  2. Point of View: Unbridle biomedical research from the laboratory cage

    Garet P Lahvis
    Recent advances in technology now make it possible to carry out biomedical research on animals living in the wild, or captive animals living in naturalistic conditions.

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